CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & RDfolder [.zip] - may take several seconds...


Overview

Metric PPfold(20) RDfolder
MCC 0.710 > 0.407
Average MCC ± 95% Confidence Intervals 0.690 ± 0.116 > 0.407 ± 0.209
Sensitivity 0.552 > 0.295
Positive Predictive Value 0.918 > 0.574
Total TP 101 > 54
Total TN 15992 < 16008
Total FP 11 < 43
Total FP CONTRA 0 < 3
Total FP INCONS 9 < 37
Total FP COMP 2 < 3
Total FN 82 < 129
P-value 0.0

^top




Performance plots


  1. Comparison of performance of PPfold(20) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and RDfolder).

^top





Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 101
Total TN 15992
Total FP 11
Total FP CONTRA 0
Total FP INCONS 9
Total FP COMP 2
Total FN 82
Total Scores
MCC 0.710
Average MCC ± 95% Confidence Intervals 0.690 ± 0.116
Sensitivity 0.552
Positive Predictive Value 0.918
Nr of predictions 6

^top



2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.86 0.74 1.00 20 2983 1 0 0 1 7
3RKF_A 0.73 0.56 0.95 19 2191 1 0 1 0 15
3SD1_A 0.68 0.52 0.88 22 3891 3 0 3 0 20
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.56 0.37 0.88 7 1267 1 0 1 0 12
4ENC_A 0.58 0.42 0.80 8 1316 2 0 2 0 11

^top



Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 54
Total TN 16008
Total FP 43
Total FP CONTRA 3
Total FP INCONS 37
Total FP COMP 3
Total FN 129
Total Scores
MCC 0.407
Average MCC ± 95% Confidence Intervals 0.407 ± 0.209
Sensitivity 0.295
Positive Predictive Value 0.574
Nr of predictions 6

^top



2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.18 0.15 0.22 4 2985 16 2 12 2 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.30 0.17 0.54 7 3903 6 0 6 0 35
4AOB_A 0.35 0.26 0.48 11 4348 13 1 11 1 31
4ENB_A 0.43 0.32 0.60 6 1265 4 0 4 0 13
4ENC_A 0.43 0.32 0.60 6 1316 4 0 4 0 13

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.