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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric PPfold(20) RNASLOpt
MCC 0.616 > 0.467
Average MCC ± 95% Confidence Intervals 0.572 ± 0.277 > 0.514 ± 0.309
Sensitivity 0.473 > 0.383
Positive Predictive Value 0.806 > 0.577
Total TP 79 > 64
Total TN 25795 > 25782
Total FP 24 < 53
Total FP CONTRA 0 < 11
Total FP INCONS 19 < 36
Total FP COMP 5 < 6
Total FN 88 < 103
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and RNASLOpt).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 79
Total TN 25795
Total FP 24
Total FP CONTRA 0
Total FP INCONS 19
Total FP COMP 5
Total FN 88
Total Scores
MCC 0.616
Average MCC ± 95% Confidence Intervals 0.572 ± 0.277
Sensitivity 0.473
Positive Predictive Value 0.806
Nr of predictions 5

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.77 0.63 0.94 34 7104 2 0 2 0 20
4A1C_2 0.21 0.15 0.29 5 11764 16 0 12 4 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.56 0.37 0.88 7 1267 1 0 1 0 12
4ENC_A 0.58 0.42 0.80 8 1316 2 0 2 0 11

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 64
Total TN 25782
Total FP 53
Total FP CONTRA 11
Total FP INCONS 36
Total FP COMP 6
Total FN 103
Total Scores
MCC 0.467
Average MCC ± 95% Confidence Intervals 0.514 ± 0.309
Sensitivity 0.383
Positive Predictive Value 0.577
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.