CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(seed) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric PPfold(seed) Mastr(seed)
MCC 0.102 > 0.000
Average MCC ± 95% Confidence Intervals 0.050 ± 0.095 > 0.000 ± 0.000
Sensitivity 0.020 > 0.000
Positive Predictive Value 0.538 > 0.000
Total TP 7 > 0
Total TN 42895 < 42908
Total FP 25 > 0
Total FP CONTRA 0 = 0
Total FP INCONS 6 > 0
Total FP COMP 19 > 0
Total FN 350 < 357
P-value 1.1568170475e-08

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Performance plots


  1. Comparison of performance of PPfold(seed) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(seed) and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for PPfold(seed) and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(seed) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(seed) and Mastr(seed)).

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Performance of PPfold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 7
Total TN 42895
Total FP 25
Total FP CONTRA 0
Total FP INCONS 6
Total FP COMP 19
Total FN 350
Total Scores
MCC 0.102
Average MCC ± 95% Confidence Intervals 0.050 ± 0.095
Sensitivity 0.020
Positive Predictive Value 0.538
Nr of predictions 11

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.30 0.75 6 1532 2 0 2 0 14
3AMU_B 0.00 0.00 0.00 0 3003 0 0 0 0 27
3J16_L 0.00 0.00 0.00 0 2775 0 0 0 0 30
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
3UZL_B 0.00 0.00 0.00 0 3570 0 0 0 0 37
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4A1C_2 0.08 0.03 0.20 1 11776 23 0 4 19 32
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 42908
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 357
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 11

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.00 0.00 0.00 0 1540 0 0 0 0 20
3AMU_B 0.00 0.00 0.00 0 3003 0 0 0 0 27
3J16_L 0.00 0.00 0.00 0 2775 0 0 0 0 30
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
3UZL_B 0.00 0.00 0.00 0 3570 0 0 0 0 37
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.