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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt Mastr(seed)
MCC 0.474 > 0.000
Average MCC ± 95% Confidence Intervals 0.505 ± 0.158 > 0.000 ± 0.000
Sensitivity 0.374 > 0.000
Positive Predictive Value 0.609 > 0.000
Total TP 95 > 0
Total TN 33622 < 33778
Total FP 67 > 0
Total FP CONTRA 11 > 0
Total FP INCONS 50 > 0
Total FP COMP 6 > 0
Total FN 159 < 254
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and Mastr(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and Mastr(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 95
Total TN 33622
Total FP 67
Total FP CONTRA 11
Total FP INCONS 50
Total FP COMP 6
Total FN 159
Total Scores
MCC 0.474
Average MCC ± 95% Confidence Intervals 0.505 ± 0.158
Sensitivity 0.374
Positive Predictive Value 0.609
Nr of predictions 8

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.35 0.64 7 1529 4 0 4 0 13
3J16_L 0.53 0.40 0.71 12 2758 5 0 5 0 18
3UZL_B 0.48 0.32 0.71 12 3553 5 0 5 0 25
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 33778
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 254
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 8

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.00 0.00 0.00 0 1540 0 0 0 0 20
3J16_L 0.00 0.00 0.00 0 2775 0 0 0 0 30
3UZL_B 0.00 0.00 0.00 0 3570 0 0 0 0 37
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.