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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt RNASampler(seed)
MCC 0.295 > 0.198
Average MCC ± 95% Confidence Intervals 0.347 ± 1.527 > 0.150 ± 2.027
Sensitivity 0.283 > 0.151
Positive Predictive Value 0.313 > 0.267
Total TP 15 > 8
Total TN 13273 < 13291
Total FP 39 > 30
Total FP CONTRA 8 > 0
Total FP INCONS 25 > 22
Total FP COMP 6 < 8
Total FN 38 < 45
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and RNASampler(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 15
Total TN 13273
Total FP 39
Total FP CONTRA 8
Total FP INCONS 25
Total FP COMP 6
Total FN 38
Total Scores
MCC 0.295
Average MCC ± 95% Confidence Intervals 0.347 ± 1.527
Sensitivity 0.283
Positive Predictive Value 0.313
Nr of predictions 2

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.35 0.64 7 1529 4 0 4 0 13
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 8
Total TN 13291
Total FP 30
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 8
Total FN 45
Total Scores
MCC 0.198
Average MCC ± 95% Confidence Intervals 0.150 ± 2.027
Sensitivity 0.151
Positive Predictive Value 0.267
Nr of predictions 2

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.