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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt TurboFold(seed)
MCC 0.467 > 0.460
Average MCC ± 95% Confidence Intervals 0.506 ± 0.235 > 0.454 ± 0.321
Sensitivity 0.380 = 0.380
Positive Predictive Value 0.582 > 0.563
Total TP 71 = 71
Total TN 27311 > 27307
Total FP 57 < 65
Total FP CONTRA 11 > 7
Total FP INCONS 40 < 48
Total FP COMP 6 < 10
Total FN 116 = 116
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and TurboFold(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 71
Total TN 27311
Total FP 57
Total FP CONTRA 11
Total FP INCONS 40
Total FP COMP 6
Total FN 116
Total Scores
MCC 0.467
Average MCC ± 95% Confidence Intervals 0.506 ± 0.235
Sensitivity 0.380
Positive Predictive Value 0.582
Nr of predictions 6

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.35 0.64 7 1529 4 0 4 0 13
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 71
Total TN 27307
Total FP 65
Total FP CONTRA 7
Total FP INCONS 48
Total FP COMP 10
Total FN 116
Total Scores
MCC 0.460
Average MCC ± 95% Confidence Intervals 0.454 ± 0.321
Sensitivity 0.380
Positive Predictive Value 0.563
Nr of predictions 6

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.15 0.15 0.15 5 11748 37 3 25 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.