CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric RNASampler(20) RNASLOpt
MCC 0.569 > 0.467
Average MCC ± 95% Confidence Intervals 0.575 ± 0.289 > 0.514 ± 0.309
Sensitivity 0.419 > 0.383
Positive Predictive Value 0.778 > 0.577
Total TP 70 > 64
Total TN 25803 > 25782
Total FP 34 < 53
Total FP CONTRA 0 < 11
Total FP INCONS 20 < 36
Total FP COMP 14 > 6
Total FN 97 < 103
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and RNASLOpt).

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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 70
Total TN 25803
Total FP 34
Total FP CONTRA 0
Total FP INCONS 20
Total FP COMP 14
Total FN 97
Total Scores
MCC 0.569
Average MCC ± 95% Confidence Intervals 0.575 ± 0.289
Sensitivity 0.419
Positive Predictive Value 0.778
Nr of predictions 5

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.74 0.56 1.00 30 7110 0 0 0 0 24
4A1C_2 0.18 0.15 0.23 5 11759 30 0 17 13 28
4AOB_A 0.58 0.40 0.85 17 4351 4 0 3 1 25
4ENB_A 0.60 0.37 1.00 7 1268 0 0 0 0 12
4ENC_A 0.76 0.58 1.00 11 1315 0 0 0 0 8

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 64
Total TN 25782
Total FP 53
Total FP CONTRA 11
Total FP INCONS 36
Total FP COMP 6
Total FN 103
Total Scores
MCC 0.467
Average MCC ± 95% Confidence Intervals 0.514 ± 0.309
Sensitivity 0.383
Positive Predictive Value 0.577
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.