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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) CRWrnafold
MCC 0.357 > 0.262
Average MCC ± 95% Confidence Intervals 0.299 ± 0.753 > 0.215 ± 0.685
Sensitivity 0.253 = 0.253
Positive Predictive Value 0.511 > 0.279
Total TP 24 = 24
Total TN 17190 > 17151
Total FP 31 < 71
Total FP CONTRA 0 < 8
Total FP INCONS 23 < 54
Total FP COMP 8 < 9
Total FN 71 = 71
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and CRWrnafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and CRWrnafold).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 24
Total TN 17190
Total FP 31
Total FP CONTRA 0
Total FP INCONS 23
Total FP COMP 8
Total FN 71
Total Scores
MCC 0.357
Average MCC ± 95% Confidence Intervals 0.299 ± 0.753
Sensitivity 0.253
Positive Predictive Value 0.511
Nr of predictions 3

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 24
Total TN 17151
Total FP 71
Total FP CONTRA 8
Total FP INCONS 54
Total FP COMP 9
Total FN 71
Total Scores
MCC 0.262
Average MCC ± 95% Confidence Intervals 0.215 ± 0.685
Sensitivity 0.253
Positive Predictive Value 0.279
Nr of predictions 3

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
3SD1_A 0.52 0.45 0.61 19 3885 12 2 10 0 23
4A1C_2 0.13 0.15 0.13 5 11741 44 4 31 9 28

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.