CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of Fold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & Fold [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) Fold
MCC 0.467 > 0.365
Average MCC ± 95% Confidence Intervals 0.423 ± 0.366 > 0.351 ± 0.392
Sensitivity 0.341 = 0.341
Positive Predictive Value 0.644 > 0.397
Total TP 56 = 56
Total TN 31764 > 31710
Total FP 43 < 108
Total FP CONTRA 2 < 11
Total FP INCONS 29 < 74
Total FP COMP 12 < 23
Total FN 108 = 108
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and Fold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and Fold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and Fold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and Fold).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 56
Total TN 31764
Total FP 43
Total FP CONTRA 2
Total FP INCONS 29
Total FP COMP 12
Total FN 108
Total Scores
MCC 0.467
Average MCC ± 95% Confidence Intervals 0.423 ± 0.366
Sensitivity 0.341
Positive Predictive Value 0.644
Nr of predictions 5

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3O58_3 0.45 0.34 0.60 12 12383 12 2 6 4 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Performance of Fold - scored lower in this pairwise comparison

1. Total counts & total scores for Fold

Total Base Pair Counts
Total TP 56
Total TN 31710
Total FP 108
Total FP CONTRA 11
Total FP INCONS 74
Total FP COMP 23
Total FN 108
Total Scores
MCC 0.365
Average MCC ± 95% Confidence Intervals 0.351 ± 0.392
Sensitivity 0.341
Positive Predictive Value 0.397
Nr of predictions 5

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2. Individual counts for Fold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
3O58_3 0.29 0.31 0.28 11 12363 41 3 26 12 24
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.57 0.48 0.69 20 3887 9 1 8 0 22
4A1C_2 0.14 0.15 0.14 5 11744 43 5 27 11 28

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.