CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) Multilign(seed)
MCC 0.532 > 0.509
Average MCC ± 95% Confidence Intervals 0.451 ± 1.011 > 0.435 ± 0.994
Sensitivity 0.375 < 0.406
Positive Predictive Value 0.766 > 0.650
Total TP 36 < 39
Total TN 7620 > 7607
Total FP 11 < 21
Total FP CONTRA 0 < 2
Total FP INCONS 11 < 19
Total FP COMP 0 = 0
Total FN 60 > 57
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and Multilign(seed)).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 36
Total TN 7620
Total FP 11
Total FP CONTRA 0
Total FP INCONS 11
Total FP COMP 0
Total FN 60
Total Scores
MCC 0.532
Average MCC ± 95% Confidence Intervals 0.451 ± 1.011
Sensitivity 0.375
Positive Predictive Value 0.766
Nr of predictions 3

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 39
Total TN 7607
Total FP 21
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 0
Total FN 57
Total Scores
MCC 0.509
Average MCC ± 95% Confidence Intervals 0.435 ± 0.994
Sensitivity 0.406
Positive Predictive Value 0.650
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1528 12 1 11 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.