CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & RDfolder [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) RDfolder
MCC 0.644 > 0.541
Average MCC ± 95% Confidence Intervals 0.630 ± 0.351 > 0.553 ± 0.376
Sensitivity 0.474 > 0.406
Positive Predictive Value 0.883 > 0.732
Total TP 83 > 71
Total TN 13980 > 13977
Total FP 11 < 26
Total FP CONTRA 0 < 2
Total FP INCONS 11 < 24
Total FP COMP 0 = 0
Total FN 92 < 104
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and RDfolder).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 83
Total TN 13980
Total FP 11
Total FP CONTRA 0
Total FP INCONS 11
Total FP COMP 0
Total FN 92
Total Scores
MCC 0.644
Average MCC ± 95% Confidence Intervals 0.630 ± 0.351
Sensitivity 0.474
Positive Predictive Value 0.883
Nr of predictions 6

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3A3A_A 0.70 0.49 1.00 18 3637 0 0 0 0 19
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26

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Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 71
Total TN 13977
Total FP 26
Total FP CONTRA 2
Total FP INCONS 24
Total FP COMP 0
Total FN 104
Total Scores
MCC 0.541
Average MCC ± 95% Confidence Intervals 0.553 ± 0.376
Sensitivity 0.406
Positive Predictive Value 0.732
Nr of predictions 6

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2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2LC8_A -0.01 0.00 0.00 0 1526 14 2 12 0 20
3A3A_A 0.53 0.41 0.71 15 3634 6 0 6 0 22
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.30 0.17 0.54 7 3903 6 0 6 0 35

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.