CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of RNAwolf - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & RNAwolf [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) RNAwolf
MCC 0.471 > 0.416
Average MCC ± 95% Confidence Intervals 0.415 ± 0.540 < 0.444 ± 0.424
Sensitivity 0.341 < 0.403
Positive Predictive Value 0.657 > 0.437
Total TP 44 < 52
Total TN 19381 > 19329
Total FP 31 < 76
Total FP CONTRA 0 < 10
Total FP INCONS 23 < 57
Total FP COMP 8 < 9
Total FN 85 > 77
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and RNAwolf).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and RNAwolf).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 44
Total TN 19381
Total FP 31
Total FP CONTRA 0
Total FP INCONS 23
Total FP COMP 8
Total FN 85
Total Scores
MCC 0.471
Average MCC ± 95% Confidence Intervals 0.415 ± 0.540
Sensitivity 0.341
Positive Predictive Value 0.657
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Performance of RNAwolf - scored lower in this pairwise comparison

1. Total counts & total scores for RNAwolf

Total Base Pair Counts
Total TP 52
Total TN 19329
Total FP 76
Total FP CONTRA 10
Total FP INCONS 57
Total FP COMP 9
Total FN 77
Total Scores
MCC 0.416
Average MCC ± 95% Confidence Intervals 0.444 ± 0.424
Sensitivity 0.403
Positive Predictive Value 0.437
Nr of predictions 4

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2. Individual counts for RNAwolf [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.52 0.50 0.56 10 1522 8 0 8 0 10
3RKF_A 0.72 0.62 0.84 21 2186 4 0 4 0 13
3SD1_A 0.46 0.43 0.50 18 3880 18 0 18 0 24
4A1C_2 0.08 0.09 0.08 3 11741 46 10 27 9 30

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.