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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of TurboFold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & TurboFold(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) TurboFold(20)
MCC 0.556 > 0.509
Average MCC ± 95% Confidence Intervals 0.557 ± 0.571 > 0.510 ± 0.751
Sensitivity 0.404 < 0.413
Positive Predictive Value 0.772 > 0.634
Total TP 44 < 45
Total TN 17851 > 17837
Total FP 21 < 35
Total FP CONTRA 0 < 1
Total FP INCONS 13 < 25
Total FP COMP 8 < 9
Total FN 65 > 64
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and TurboFold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and TurboFold(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and TurboFold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and TurboFold(20)).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 44
Total TN 17851
Total FP 21
Total FP CONTRA 0
Total FP INCONS 13
Total FP COMP 8
Total FN 65
Total Scores
MCC 0.556
Average MCC ± 95% Confidence Intervals 0.557 ± 0.571
Sensitivity 0.404
Positive Predictive Value 0.772
Nr of predictions 3

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Performance of TurboFold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 45
Total TN 17837
Total FP 35
Total FP CONTRA 1
Total FP INCONS 25
Total FP COMP 9
Total FN 64
Total Scores
MCC 0.509
Average MCC ± 95% Confidence Intervals 0.510 ± 0.751
Sensitivity 0.413
Positive Predictive Value 0.634
Nr of predictions 3

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
4A1C_2 0.18 0.15 0.21 5 11757 28 0 19 9 28

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.