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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(seed) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(seed) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric RNAalifold(seed) RNASLOpt
MCC 0.472 > 0.390
Average MCC ± 95% Confidence Intervals 0.444 ± 0.347 < 0.473 ± 0.289
Sensitivity 0.293 < 0.323
Positive Predictive Value 0.765 > 0.478
Total TP 39 < 43
Total TN 20242 > 20203
Total FP 15 < 53
Total FP CONTRA 0 < 11
Total FP INCONS 12 < 36
Total FP COMP 3 < 6
Total FN 94 > 90
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(seed) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and RNASLOpt).

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Performance of RNAalifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(seed)

Total Base Pair Counts
Total TP 39
Total TN 20242
Total FP 15
Total FP CONTRA 0
Total FP INCONS 12
Total FP COMP 3
Total FN 94
Total Scores
MCC 0.472
Average MCC ± 95% Confidence Intervals 0.444 ± 0.347
Sensitivity 0.293
Positive Predictive Value 0.765
Nr of predictions 5

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2. Individual counts for RNAalifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1528 12 0 12 0 20
4A1C_2 0.39 0.15 1.00 5 11776 2 0 0 2 28
4AOB_A 0.72 0.52 1.00 22 4349 1 0 0 1 20
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 43
Total TN 20203
Total FP 53
Total FP CONTRA 11
Total FP INCONS 36
Total FP COMP 6
Total FN 90
Total Scores
MCC 0.390
Average MCC ± 95% Confidence Intervals 0.473 ± 0.289
Sensitivity 0.323
Positive Predictive Value 0.478
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.35 0.64 7 1529 4 0 4 0 13
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.