CompaRNA - on-line benchmarks of RNA structure prediction methods

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Metric	TurboFold(20)		Afold
MCC	0.501	>	0.461
Average MCC ± 95% Confidence Intervals	0.542 ± 0.794	>	0.526 ± 0.833
Sensitivity	0.395	<	0.419
Positive Predictive Value	0.642	>	0.514
Total TP	34	<	36
Total TN	15214	>	15197
Total FP	28	<	46
Total FP CONTRA	0	<	6
Total FP INCONS	19	<	28
Total FP COMP	9	<	12
Total FN	52	>	50
P-value	0.0

Comparison of performance of TurboFold(20) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Afold).
Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Afold).

Total Scores
MCC	0.501
Average MCC ± 95% Confidence Intervals	0.542 ± 0.794
Sensitivity	0.395
Positive Predictive Value	0.642
Nr of predictions	3

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
3RKF_A	Purine links to Rfam database...	0.76	0.59	1.00	20	2191	0	0	0	0	14
4A1C_2	5_8S_rRNA links to Rfam database...	0.18	0.15	0.21	5	11757	28	0	19	9	28
4ENB_A	crcB links to Rfam database...	0.69	0.47	1.00	9	1266	0	0	0	0	10

Total Scores
MCC	0.461
Average MCC ± 95% Confidence Intervals	0.526 ± 0.833
Sensitivity	0.419
Positive Predictive Value	0.514
Nr of predictions	3

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
3RKF_A	Purine links to Rfam database...	0.76	0.59	1.00	20	2191	0	0	0	0	14
4A1C_2	5_8S_rRNA links to Rfam database...	0.14	0.15	0.14	5	11745	43	5	26	12	28
4ENB_A	crcB links to Rfam database...	0.67	0.58	0.79	11	1261	3	1	2	0	8

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.