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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of MXScarna(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & MXScarna(20) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) MXScarna(20)
MCC 0.594 > 0.586
Average MCC ± 95% Confidence Intervals 0.602 ± 0.154 > 0.566 ± 0.193
Sensitivity 0.470 < 0.474
Positive Predictive Value 0.756 > 0.731
Total TP 127 < 128
Total TN 34855 > 34848
Total FP 53 < 68
Total FP CONTRA 3 < 6
Total FP INCONS 38 < 41
Total FP COMP 12 < 21
Total FN 143 > 142
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and MXScarna(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and MXScarna(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and MXScarna(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and MXScarna(20)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 127
Total TN 34855
Total FP 53
Total FP CONTRA 3
Total FP INCONS 38
Total FP COMP 12
Total FN 143
Total Scores
MCC 0.594
Average MCC ± 95% Confidence Intervals 0.602 ± 0.154
Sensitivity 0.470
Positive Predictive Value 0.756
Nr of predictions 8

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.70 0.59 0.84 16 2984 5 0 3 2 11
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
4A1C_2 0.18 0.15 0.21 5 11757 28 0 19 9 28
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of MXScarna(20) - scored lower in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 128
Total TN 34848
Total FP 68
Total FP CONTRA 6
Total FP INCONS 41
Total FP COMP 21
Total FN 142
Total Scores
MCC 0.586
Average MCC ± 95% Confidence Intervals 0.566 ± 0.193
Sensitivity 0.474
Positive Predictive Value 0.731
Nr of predictions 8

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.86 0.74 1.00 20 2983 2 0 0 2 7
3RKF_A 0.72 0.53 1.00 18 2193 0 0 0 0 16
3SD1_A 0.63 0.55 0.74 23 3885 8 2 6 0 19
4A1C_2 0.18 0.15 0.21 5 11757 36 2 17 17 28
4A1C_3 0.64 0.56 0.75 30 7100 11 2 8 1 24
4AOB_A 0.62 0.55 0.72 23 4339 10 0 9 1 19
4ENB_A 0.26 0.11 0.67 2 1272 1 0 1 0 17
4ENC_A 0.60 0.37 1.00 7 1319 0 0 0 0 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.