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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Murlet(seed)
MCC 0.547 > 0.520
Average MCC ± 95% Confidence Intervals 0.570 ± 0.217 > 0.525 ± 0.052
Sensitivity 0.423 > 0.296
Positive Predictive Value 0.714 < 0.918
Total TP 80 > 56
Total TN 24768 < 24819
Total FP 42 > 6
Total FP CONTRA 3 > 1
Total FP INCONS 29 > 4
Total FP COMP 10 > 1
Total FN 109 < 133
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 80
Total TN 24768
Total FP 42
Total FP CONTRA 3
Total FP INCONS 29
Total FP COMP 10
Total FN 109
Total Scores
MCC 0.547
Average MCC ± 95% Confidence Intervals 0.570 ± 0.217
Sensitivity 0.423
Positive Predictive Value 0.714
Nr of predictions 6

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
4A1C_2 0.18 0.15 0.21 5 11757 28 0 19 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 56
Total TN 24819
Total FP 6
Total FP CONTRA 1
Total FP INCONS 4
Total FP COMP 1
Total FN 133
Total Scores
MCC 0.520
Average MCC ± 95% Confidence Intervals 0.525 ± 0.052
Sensitivity 0.296
Positive Predictive Value 0.918
Nr of predictions 6

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.