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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & RDfolder [.zip] - may take several seconds...


Overview

Metric TurboFold(20) RDfolder
MCC 0.647 > 0.407
Average MCC ± 95% Confidence Intervals 0.658 ± 0.080 > 0.407 ± 0.209
Sensitivity 0.497 > 0.295
Positive Predictive Value 0.850 > 0.574
Total TP 91 > 54
Total TN 15995 < 16008
Total FP 19 < 43
Total FP CONTRA 3 = 3
Total FP INCONS 13 < 37
Total FP COMP 3 = 3
Total FN 92 < 129
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and RDfolder).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 91
Total TN 15995
Total FP 19
Total FP CONTRA 3
Total FP INCONS 13
Total FP COMP 3
Total FN 92
Total Scores
MCC 0.647
Average MCC ± 95% Confidence Intervals 0.658 ± 0.080
Sensitivity 0.497
Positive Predictive Value 0.850
Nr of predictions 6

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.70 0.59 0.84 16 2984 5 0 3 2 11
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 54
Total TN 16008
Total FP 43
Total FP CONTRA 3
Total FP INCONS 37
Total FP COMP 3
Total FN 129
Total Scores
MCC 0.407
Average MCC ± 95% Confidence Intervals 0.407 ± 0.209
Sensitivity 0.295
Positive Predictive Value 0.574
Nr of predictions 6

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2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.18 0.15 0.22 4 2985 16 2 12 2 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.30 0.17 0.54 7 3903 6 0 6 0 35
4AOB_A 0.35 0.26 0.48 11 4348 13 1 11 1 31
4ENB_A 0.43 0.32 0.60 6 1265 4 0 4 0 13
4ENC_A 0.43 0.32 0.60 6 1316 4 0 4 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.