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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric TurboFold(20) RNASLOpt
MCC 0.542 > 0.467
Average MCC ± 95% Confidence Intervals 0.552 ± 0.270 > 0.514 ± 0.309
Sensitivity 0.425 > 0.383
Positive Predictive Value 0.696 > 0.577
Total TP 71 > 64
Total TN 25791 > 25782
Total FP 41 < 53
Total FP CONTRA 2 < 11
Total FP INCONS 29 < 36
Total FP COMP 10 > 6
Total FN 96 < 103
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and RNASLOpt).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 71
Total TN 25791
Total FP 41
Total FP CONTRA 2
Total FP INCONS 29
Total FP COMP 10
Total FN 96
Total Scores
MCC 0.542
Average MCC ± 95% Confidence Intervals 0.552 ± 0.270
Sensitivity 0.425
Positive Predictive Value 0.696
Nr of predictions 5

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.18 0.15 0.21 5 11757 28 0 19 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 64
Total TN 25782
Total FP 53
Total FP CONTRA 11
Total FP INCONS 36
Total FP COMP 6
Total FN 103
Total Scores
MCC 0.467
Average MCC ± 95% Confidence Intervals 0.514 ± 0.309
Sensitivity 0.383
Positive Predictive Value 0.577
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.