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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of UNAFold - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & UNAFold [.zip] - may take several seconds...


Overview

Metric TurboFold(20) UNAFold
MCC 0.594 > 0.556
Average MCC ± 95% Confidence Intervals 0.602 ± 0.154 > 0.558 ± 0.184
Sensitivity 0.470 < 0.474
Positive Predictive Value 0.756 > 0.660
Total TP 127 < 128
Total TN 34855 > 34829
Total FP 53 < 80
Total FP CONTRA 3 < 11
Total FP INCONS 38 < 55
Total FP COMP 12 < 14
Total FN 143 > 142
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and UNAFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and UNAFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and UNAFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and UNAFold).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 127
Total TN 34855
Total FP 53
Total FP CONTRA 3
Total FP INCONS 38
Total FP COMP 12
Total FN 143
Total Scores
MCC 0.594
Average MCC ± 95% Confidence Intervals 0.602 ± 0.154
Sensitivity 0.470
Positive Predictive Value 0.756
Nr of predictions 8

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.70 0.59 0.84 16 2984 5 0 3 2 11
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
4A1C_2 0.18 0.15 0.21 5 11757 28 0 19 9 28
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of UNAFold - scored lower in this pairwise comparison

1. Total counts & total scores for UNAFold

Total Base Pair Counts
Total TP 128
Total TN 34829
Total FP 80
Total FP CONTRA 11
Total FP INCONS 55
Total FP COMP 14
Total FN 142
Total Scores
MCC 0.556
Average MCC ± 95% Confidence Intervals 0.558 ± 0.184
Sensitivity 0.474
Positive Predictive Value 0.660
Nr of predictions 8

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2. Individual counts for UNAFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.70 0.59 0.84 16 2984 5 0 3 2 11
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.64 0.52 0.79 22 3888 6 1 5 0 20
4A1C_2 0.14 0.15 0.14 5 11745 42 5 26 11 28
4A1C_3 0.70 0.59 0.82 32 7101 7 1 6 0 22
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.70 0.58 0.85 11 1262 2 1 1 0 8
4ENC_A 0.32 0.26 0.42 5 1314 7 1 6 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.