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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) Mastr(seed)
MCC 0.517 > 0.000
Average MCC ± 95% Confidence Intervals 0.510 ± 0.236 > 0.000 ± 0.000
Sensitivity 0.422 > 0.000
Positive Predictive Value 0.642 > 0.000
Total TP 111 > 0
Total TN 33387 < 33560
Total FP 72 > 0
Total FP CONTRA 8 > 0
Total FP INCONS 54 > 0
Total FP COMP 10 > 0
Total FN 152 < 263
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and Mastr(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and Mastr(seed)).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 111
Total TN 33387
Total FP 72
Total FP CONTRA 8
Total FP INCONS 54
Total FP COMP 10
Total FN 152
Total Scores
MCC 0.517
Average MCC ± 95% Confidence Intervals 0.510 ± 0.236
Sensitivity 0.422
Positive Predictive Value 0.642
Nr of predictions 8

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.59 0.48 0.74 20 3889 7 1 6 0 22
4A1C_2 0.15 0.15 0.15 5 11748 37 3 25 9 28
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 33560
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 263
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 8

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.00 0.00 0.00 0 1540 0 0 0 0 20
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.