CompaRNA - on-line benchmarks of RNA structure prediction methods

Laboratory of Structural Bioinformatics @ Adam Mickiewicz University in Poznan

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Overview

Metric	Afold		NanoFolder
MCC	0.559	>	0.188
Average MCC ± 95% Confidence Intervals	0.562 ± 0.044	>	0.263 ± 0.042
Sensitivity	0.551	>	0.218
Positive Predictive Value	0.569	>	0.165
Total TP	5685	>	2246
Total TN	5321703	>	5318083
Total FP	5000	<	11771
Total FP CONTRA	617	<	1845
Total FP INCONS	3695	<	9526
Total FP COMP	688	>	400
Total FN	4640	<	8079
P-value	3.56938820447e-08

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Performance plots

Comparison of performance of Afold and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Afold and NanoFolder).
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Afold and NanoFolder).
Comparison of average Matthews Correlation Coefficients (MCCs) for Afold and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Afold and NanoFolder).

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Performance of Afold - scored higher in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP	5685
Total TN	5321703
Total FP	5000
Total FP CONTRA	617
Total FP INCONS	3695
Total FP COMP	688
Total FN	4640

Total Scores
MCC	0.559
Average MCC ± 95% Confidence Intervals	0.562 ± 0.044
Sensitivity	0.551
Positive Predictive Value	0.569
Nr of predictions	160

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2. Individual counts for Afold [ download as .csv ]

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
ASE_00017	RNaseP_nuc links to Rfam database...	0.26	0.28	0.24	18	50965	74	6	51	17	46
ASE_00083	RNaseP_bact_a links to Rfam database...	0.71	0.67	0.76	74	62383	32	1	23	8	36
ASE_00122	RNaseP_bact_a links to Rfam database...	0.28	0.27	0.29	24	43283	60	4	54	2	64
ASE_00185	RNaseP_bact_a links to Rfam database...	0.72	0.70	0.74	89	73416	38	6	25	7	39
ASE_00190	RNaseP_bact_b links to Rfam database...	0.49	0.46	0.52	41	45372	44	7	31	6	49
ASE_00191	RNaseP_arch links to Rfam database...	0.56	0.52	0.59	32	29592	32	1	21	10	29
ASE_00196	RNaseP_arch links to Rfam database...	0.76	0.75	0.77	56	31553	21	2	15	4	19
ASE_00221	RNaseP_bact_a links to Rfam database...	0.49	0.45	0.54	53	64522	48	3	42	3	64
ASE_00227	RNaseP_bact_a links to Rfam database...	0.25	0.23	0.27	31	78888	84	6	78	0	102
ASE_00228	RNaseP_bact_a links to Rfam database...	0.52	0.53	0.50	46	46879	46	14	32	0	40
ASE_00229	RNaseP_bact_a links to Rfam database...	0.61	0.61	0.62	53	42400	33	8	25	0	34
ASE_00231	RNaseP_bact_a links to Rfam database...	0.65	0.65	0.65	62	47800	33	5	28	0	34
ASE_00234	RNaseP_bact_a links to Rfam database...	0.58	0.53	0.62	69	75355	47	3	39	5	60
ASE_00238	RNaseP_bact_a links to Rfam database...	0.59	0.59	0.60	67	64150	50	2	42	6	47
ASE_00254	RNaseP_bact_a links to Rfam database...	0.49	0.46	0.52	38	36783	39	4	31	4	44
ASE_00255	RNaseP_bact_a links to Rfam database...	0.64	0.62	0.66	80	74570	45	7	34	4	50
ASE_00257	RNaseP_bact_a links to Rfam database...	0.55	0.55	0.55	53	50944	47	4	39	4	44
ASE_00267	RNaseP_bact_a links to Rfam database...	0.32	0.31	0.34	27	45070	62	5	48	9	61
ASE_00270	RNaseP_bact_a links to Rfam database...	0.76	0.73	0.80	94	72272	29	4	20	5	34
ASE_00274	RNaseP_bact_a links to Rfam database...	0.45	0.44	0.46	45	55513	54	10	43	1	58
ASE_00277	RNaseP_bact_a links to Rfam database...	0.38	0.38	0.38	35	48112	61	9	49	3	56
ASE_00279	RNaseP_bact_a links to Rfam database...	0.68	0.66	0.71	67	53206	35	3	25	7	34
ASE_00285	RNaseP_bact_a links to Rfam database...	0.75	0.70	0.80	86	68899	28	3	18	7	36
ASE_00287	RNaseP_bact_a links to Rfam database...	0.59	0.55	0.63	57	54856	39	2	31	6	46
ASE_00294	RNaseP_bact_a links to Rfam database...	0.74	0.68	0.80	117	114335	32	2	27	3	54
ASE_00295	RNaseP_bact_a links to Rfam database...	0.63	0.60	0.66	79	73801	42	8	32	2	52
ASE_00298	RNaseP_bact_a links to Rfam database...	0.28	0.27	0.29	31	67420	79	9	68	2	82
ASE_00321	RNaseP_bact_b links to Rfam database...	0.40	0.40	0.41	35	54530	57	7	43	7	53
ASE_00340	RNaseP_bact_a links to Rfam database...	0.76	0.73	0.78	62	45977	26	6	11	9	23
ASE_00343	RNaseP_bact_a links to Rfam database...	0.34	0.35	0.34	39	83321	88	9	67	12	74
ASE_00344	-	0.95	0.93	0.96	52	27207	21	0	2	19	4
ASE_00350	-	0.87	0.85	0.90	44	29597	31	0	5	26	8
ASE_00367	RNaseP_bact_a links to Rfam database...	0.28	0.29	0.27	25	42979	68	8	59	1	61
ASE_00370	RNaseP_bact_a links to Rfam database...	0.63	0.63	0.62	53	41820	33	7	25	1	31
ASE_00372	RNaseP_bact_a links to Rfam database...	0.63	0.62	0.65	62	51907	39	6	28	5	38
ASE_00375	RNaseP_bact_a links to Rfam database...	0.70	0.66	0.74	73	60280	31	1	24	6	37
ASE_00376	RNaseP_bact_a links to Rfam database...	0.48	0.46	0.50	48	56857	52	4	44	4	57
ASE_00386	RNaseP_bact_a links to Rfam database...	0.65	0.65	0.65	62	50307	41	3	31	7	34
ASE_00393	RNaseP_bact_a links to Rfam database...	0.37	0.35	0.39	33	47811	58	2	49	7	60
ASE_00413	RNaseP_bact_a links to Rfam database...	0.55	0.58	0.52	47	44461	44	13	30	1	34
ASE_00416	RNaseP_bact_a links to Rfam database...	0.65	0.61	0.68	78	77307	43	0	36	7	49
ASE_00417	RNaseP_arch links to Rfam database...	0.36	0.37	0.35	37	54508	73	10	60	3	63
ASE_00422	RNaseP_bact_a links to Rfam database...	0.44	0.44	0.45	41	46880	56	5	45	6	53
ASE_00427	RNaseP_nuc links to Rfam database...	0.15	0.20	0.12	9	40678	81	17	51	13	37
ASE_00428	RNaseP_bact_a links to Rfam database...	0.51	0.50	0.53	62	76520	58	5	49	4	63
ASE_00429	-	0.43	0.44	0.43	29	28136	40	8	30	2	37
ASE_00430	RNaseP_bact_a links to Rfam database...	0.64	0.63	0.66	61	46878	39	5	27	7	36
ASE_00434	RNaseP_bact_b links to Rfam database...	0.61	0.60	0.62	66	68159	48	7	33	8	44
ASE_00437	RNaseP_bact_a links to Rfam database...	0.42	0.39	0.46	53	79285	64	4	59	1	82
ASE_00451	RNaseP_bact_a links to Rfam database...	0.61	0.57	0.66	71	70768	40	2	35	3	54
ASE_00454	RNaseP_nuc links to Rfam database...	0.48	0.48	0.48	30	43302	59	2	31	26	33
CRW_00648	-	0.61	0.64	0.59	94	137915	75	17	49	9	54
CRW_00654	-	0.70	0.68	0.72	84	78094	38	4	28	6	40
CRW_00663	-	0.14	0.15	0.13	9	26039	61	6	52	3	52
CRW_00664	-	0.05	0.05	0.04	4	53536	92	20	68	4	74
CRW_00671	Intron_gpI links to Rfam database...	0.66	0.64	0.68	75	62725	41	8	27	6	42
CRW_00672	Intron_gpI links to Rfam database...	0.74	0.73	0.74	81	72281	36	10	18	8	30
CRW_00674	Intron_gpI links to Rfam database...	0.55	0.55	0.55	68	83312	61	8	48	5	56
CRW_00676	Intron_gpI links to Rfam database...	0.54	0.56	0.52	64	93406	75	17	41	17	51
CRW_00685	-	0.38	0.42	0.34	44	156952	121	20	64	37	62
CRW_00721	-	0.52	0.60	0.46	41	58563	65	19	30	16	27
CRW_00756	-	0.48	0.50	0.47	86	194817	109	14	83	12	86
CRW_01539	5S_rRNA links to Rfam database...	0.81	0.76	0.88	28	7108	10	0	4	6	9
CRW_01563	5S_rRNA links to Rfam database...	0.57	0.51	0.63	19	6873	12	2	9	1	18
CRW_01583	5S_rRNA links to Rfam database...	0.79	0.76	0.82	28	7106	10	0	6	4	9
CRW_01590	5S_rRNA links to Rfam database...	0.21	0.22	0.21	8	7102	30	6	24	0	29
CRW_01603	5S_rRNA links to Rfam database...	0.82	0.78	0.85	29	7106	8	0	5	3	8
PDB_00011	-	0.91	0.83	1.00	10	266	0	0	0	0	2
PDB_00017	-	0.77	0.60	1.00	9	694	0	0	0	0	6
PDB_00036	-	-0.01	0.00	0.00	0	3461	27	1	24	2	27
PDB_00078	-	0.47	0.45	0.50	52	49665	53	6	47	0	63
PDB_00113	-	0.94	0.89	1.00	8	223	0	0	0	0	1
PDB_00119	-	0.95	0.90	1.00	9	244	0	0	0	0	1
PDB_00136	-	0.76	0.73	0.79	19	2391	7	0	5	2	7
PDB_00160	-	0.94	0.89	1.00	8	268	0	0	0	0	1
PDB_00178	-	0.90	0.82	1.00	9	519	1	0	0	1	2
PDB_00221	-	0.88	0.78	1.00	7	246	0	0	0	0	2
PDB_00278	-	0.13	0.13	0.13	9	24907	60	6	54	0	63
PDB_00312	-	1.00	1.00	1.00	9	426	0	0	0	0	0
PDB_00341	-	-0.02	0.00	0.00	0	691	12	0	12	0	16
PDB_00349	-	0.64	0.64	0.64	9	932	5	0	5	0	5
PDB_00417	-	0.10	0.11	0.11	6	14141	49	6	43	0	50
PDB_00527	-	-0.01	0.00	0.00	0	297	6	0	3	3	5
PDB_00565	-	0.77	0.70	0.85	35	8087	7	0	6	1	15
PDB_00570	-	-0.01	0.00	0.00	0	2257	21	2	19	0	22
PDB_00571	tRNA links to Rfam database...	-0.01	0.00	0.00	0	3302	20	5	14	1	25
PDB_00573	-	0.40	0.41	0.39	14	6634	24	4	18	2	20
PDB_00584	-	0.47	0.41	0.54	7	1472	6	0	6	0	10
PDB_00701	-	0.47	0.46	0.49	50	45348	54	5	48	1	59
PDB_00725	-	0.74	0.67	0.83	10	583	2	0	2	0	5
PDB_00734	-	0.83	0.70	1.00	7	224	0	0	0	0	3
PDB_00823	-	-0.03	0.00	0.00	0	185	5	0	5	0	9
PDB_00828	Purine links to Rfam database...	0.88	0.78	1.00	21	2464	0	0	0	0	6
PDB_00890	-	-0.02	0.00	0.00	0	689	14	2	12	0	14
PDB_00917	-	0.49	0.47	0.51	45	35157	49	4	39	6	50
PDB_01009	tRNA links to Rfam database...	0.52	0.57	0.48	12	2460	13	5	8	0	9
PDB_01051	Telomerase-cil links to Rfam database...	0.75	0.69	0.82	9	892	6	0	2	4	4
PDB_01074	-	-0.01	0.00	0.00	0	2746	29	3	26	0	25
PDB_01130	-	-0.01	0.00	0.00	0	1746	24	6	18	0	20
PDB_01193	-	0.42	0.41	0.43	62	105885	92	14	69	9	89
PDB_01199	-	0.18	0.17	0.22	4	2127	14	0	14	0	20
RFA_00416	Hammerhead_3 links to Rfam database...	0.93	0.93	0.93	14	1470	4	0	1	3	1
RFA_00434	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1416	2	0	0	2	0
RFA_00436	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1416	2	0	0	2	0
RFA_00442	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1416	2	0	0	2	0
RFA_00446	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1471	3	0	0	3	1
RFA_00604	Telomerase-cil links to Rfam database...	0.72	0.74	0.70	26	13493	24	2	9	13	9
RFA_00620	Telomerase-cil links to Rfam database...	0.64	0.62	0.67	24	21909	26	3	9	14	15
RFA_00664	Hammerhead_1 links to Rfam database...	0.07	0.07	0.09	1	979	11	0	10	1	13
RFA_00674	Hammerhead_1 links to Rfam database...	0.69	0.71	0.67	10	1113	6	0	5	1	4
RFA_00675	Hammerhead_1 links to Rfam database...	0.29	0.29	0.31	4	977	9	1	8	0	10
RFA_00677	Hammerhead_1 links to Rfam database...	0.42	0.43	0.43	6	976	9	0	8	1	8
RFA_00684	Hammerhead_1 links to Rfam database...	0.66	0.64	0.69	9	977	5	0	4	1	5
RFA_00703	Hammerhead_1 links to Rfam database...	0.67	0.64	0.69	9	4265	18	1	3	14	5
RFA_00716	Hammerhead_1 links to Rfam database...	0.06	0.07	0.08	1	933	12	0	12	0	13
RFA_00717	Hammerhead_1 links to Rfam database...	0.64	0.64	0.64	9	889	5	0	5	0	5
RFA_00730	s2m links to Rfam database...	0.69	0.67	0.73	8	892	4	1	2	1	4
RFA_00763	s2m links to Rfam database...	1.00	1.00	1.00	12	891	1	0	0	1	0
RFA_00765	s2m links to Rfam database...	1.00	1.00	1.00	12	891	1	0	0	1	0
RFA_00770	Corona_pk3 links to Rfam database...	0.68	0.56	0.83	10	2004	6	0	2	4	8
RFA_00773	Corona_pk3 links to Rfam database...	0.71	0.56	0.91	10	1942	5	1	0	4	8
RFA_00808	RydC links to Rfam database...	-0.01	0.00	0.00	0	2001	16	2	13	1	16
RFA_00816	R2_retro_el links to Rfam database...	0.59	0.66	0.53	27	23169	33	13	11	9	14
SPR_00030	-	0.47	0.43	0.53	9	2468	8	0	8	0	12
SPR_00331	tRNA links to Rfam database...	0.32	0.35	0.30	7	2752	16	5	11	0	13
SPR_00333	tRNA links to Rfam database...	-0.01	0.00	0.00	0	2753	22	6	16	0	21
SPR_00509	tRNA links to Rfam database...	0.97	0.95	1.00	19	2907	3	0	0	3	1
SPR_00512	tRNA links to Rfam database...	0.97	0.95	1.00	19	2907	3	0	0	3	1
SPR_00557	tRNA links to Rfam database...	0.40	0.43	0.39	9	2827	15	1	13	1	12
SRP_00005	-	0.28	0.29	0.27	7	3979	21	4	15	2	17
SRP_00038	Bacteria_small_SRP links to Rfam database...	-0.01	0.00	0.00	0	5019	31	2	29	0	33
SRP_00117	Metazoa_SRP links to Rfam database...	0.63	0.62	0.64	63	45352	39	1	35	3	39
SRP_00144	Archaea_SRP links to Rfam database...	0.74	0.74	0.74	70	46571	31	1	23	7	24
SRP_00173	Bacteria_large_SRP links to Rfam database...	0.72	0.70	0.75	63	38142	29	1	20	8	27
SRP_00193	-	0.67	0.67	0.69	24	6868	12	1	10	1	12
SRP_00197	Archaea_SRP links to Rfam database...	0.24	0.24	0.25	24	49359	72	7	65	0	77
SRP_00200	Bacteria_small_SRP links to Rfam database...	0.44	0.44	0.43	16	6866	21	2	19	0	20
SRP_00216	Bacteria_small_SRP links to Rfam database...	0.93	0.93	0.93	25	3376	3	1	1	1	2
SRP_00233	Bacteria_small_SRP links to Rfam database...	0.91	0.88	0.94	29	5120	2	0	2	0	4
SRP_00234	Bacteria_large_SRP links to Rfam database...	0.77	0.77	0.78	66	36230	25	1	18	6	20
SRP_00243	Bacteria_small_SRP links to Rfam database...	0.90	0.87	0.93	27	5122	3	0	2	1	4
SRP_00267	Metazoa_SRP links to Rfam database...	0.87	0.88	0.87	84	44454	19	0	13	6	12
SRP_00273	Bacteria_small_SRP links to Rfam database...	0.86	0.88	0.85	35	6745	8	1	5	2	5
SRP_00276	Archaea_SRP links to Rfam database...	0.86	0.85	0.86	94	50612	16	5	10	1	16
SRP_00278	Archaea_SRP links to Rfam database...	0.72	0.72	0.71	76	45949	33	4	27	2	29
SRP_00303	Bacteria_small_SRP links to Rfam database...	0.60	0.63	0.59	20	6636	14	1	13	0	12
SRP_00308	Bacteria_large_SRP links to Rfam database...	0.55	0.55	0.56	48	36229	42	9	29	4	40
SRP_00317	Metazoa_SRP links to Rfam database...	0.93	0.89	0.98	87	45061	10	0	2	8	11
SRP_00321	Archaea_SRP links to Rfam database...	0.77	0.77	0.78	83	47479	27	3	21	3	25
SRP_00322	Archaea_SRP links to Rfam database...	0.60	0.60	0.61	65	48409	43	2	40	1	44
SRP_00332	Archaea_SRP links to Rfam database...	0.90	0.90	0.91	95	50299	15	1	8	6	11
SRP_00337	Bacteria_large_SRP links to Rfam database...	0.73	0.71	0.76	65	35425	23	1	20	2	26
SRP_00338	Bacteria_small_SRP links to Rfam database...	0.92	0.92	0.92	33	5424	4	0	3	1	3
SRP_00342	Bacteria_small_SRP links to Rfam database...	0.57	0.60	0.56	15	3978	17	1	11	5	10
SRP_00354	-	0.76	0.75	0.76	70	38689	25	0	22	3	23
SRP_00355	-	0.84	0.83	0.85	80	41811	19	2	12	5	16
SRP_00383	Bacteria_small_SRP links to Rfam database...	0.12	0.13	0.13	3	3216	21	3	18	0	21
TMR_00352	tmRNA links to Rfam database...	0.42	0.45	0.39	34	95179	91	17	36	38	41
TMR_00594	tmRNA links to Rfam database...	0.20	0.20	0.20	21	79294	90	15	71	4	83
TMR_00706	tmRNA links to Rfam database...	0.50	0.50	0.50	51	66328	55	6	45	4	52

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP	2246
Total TN	5318083
Total FP	11771
Total FP CONTRA	1845
Total FP INCONS	9526
Total FP COMP	400
Total FN	8079

Total Scores
MCC	0.188
Average MCC ± 95% Confidence Intervals	0.263 ± 0.042
Sensitivity	0.218
Positive Predictive Value	0.165
Nr of predictions	160

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
ASE_00017	RNaseP_nuc links to Rfam database...	0.02	0.03	0.02	2	50914	131	38	86	7	62
ASE_00083	RNaseP_bact_a links to Rfam database...	0.22	0.25	0.20	27	62347	108	12	95	1	83
ASE_00122	RNaseP_bact_a links to Rfam database...	0.27	0.30	0.24	26	43258	84	13	68	3	62
ASE_00185	RNaseP_bact_a links to Rfam database...	0.17	0.19	0.16	24	73382	134	14	116	4	104
ASE_00190	RNaseP_bact_b links to Rfam database...	0.24	0.28	0.21	25	45334	93	14	78	1	65
ASE_00191	RNaseP_arch links to Rfam database...	0.36	0.43	0.30	26	29559	67	15	46	6	35
ASE_00196	RNaseP_arch links to Rfam database...	0.49	0.57	0.42	43	31524	62	16	43	3	32
ASE_00221	RNaseP_bact_a links to Rfam database...	0.20	0.21	0.18	25	64484	112	10	101	1	92
ASE_00227	RNaseP_bact_a links to Rfam database...	0.28	0.31	0.25	41	78840	122	20	102	0	92
ASE_00228	RNaseP_bact_a links to Rfam database...	0.05	0.06	0.04	5	46858	109	17	91	1	81
ASE_00229	RNaseP_bact_a links to Rfam database...	0.12	0.14	0.11	12	42380	97	12	82	3	75
ASE_00231	RNaseP_bact_a links to Rfam database...	0.37	0.42	0.33	40	47773	84	17	65	2	56
ASE_00234	RNaseP_bact_a links to Rfam database...	0.25	0.27	0.23	35	75315	117	10	106	1	94
ASE_00238	RNaseP_bact_a links to Rfam database...	0.26	0.30	0.23	34	64111	119	18	98	3	80
ASE_00254	RNaseP_bact_a links to Rfam database...	0.15	0.16	0.14	13	36761	88	3	79	6	69
ASE_00255	RNaseP_bact_a links to Rfam database...	0.11	0.12	0.10	16	74530	146	16	129	1	114
ASE_00257	RNaseP_bact_a links to Rfam database...	0.37	0.42	0.33	41	50917	85	15	67	3	56
ASE_00267	RNaseP_bact_a links to Rfam database...	0.00	0.00	0.00	0	45036	115	9	105	1	88
ASE_00270	RNaseP_bact_a links to Rfam database...	0.19	0.21	0.17	27	72232	132	14	117	1	101
ASE_00274	RNaseP_bact_a links to Rfam database...	0.00	0.00	0.00	0	55487	126	12	112	2	103
ASE_00277	RNaseP_bact_a links to Rfam database...	0.10	0.12	0.08	11	48071	123	23	100	0	80
ASE_00279	RNaseP_bact_a links to Rfam database...	0.14	0.16	0.13	16	53177	109	16	92	1	85
ASE_00285	RNaseP_bact_a links to Rfam database...	0.34	0.36	0.31	44	68866	98	14	82	2	78
ASE_00287	RNaseP_bact_a links to Rfam database...	0.15	0.17	0.14	17	54824	107	14	91	2	86
ASE_00294	RNaseP_bact_a links to Rfam database...	0.12	0.13	0.12	23	114287	172	11	160	1	148
ASE_00295	RNaseP_bact_a links to Rfam database...	0.14	0.16	0.13	21	73761	140	19	119	2	110
ASE_00298	RNaseP_bact_a links to Rfam database...	0.09	0.10	0.08	11	67389	129	8	120	1	102
ASE_00321	RNaseP_bact_b links to Rfam database...	0.11	0.14	0.09	12	54484	122	22	97	3	76
ASE_00340	RNaseP_bact_a links to Rfam database...	0.06	0.07	0.05	6	45943	110	13	94	3	79
ASE_00343	RNaseP_bact_a links to Rfam database...	0.14	0.17	0.12	19	83275	145	31	111	3	94
ASE_00344	-	0.30	0.38	0.24	21	27175	84	18	47	19	35
ASE_00350	-	0.00	0.00	0.00	0	29557	101	20	69	12	52
ASE_00367	RNaseP_bact_a links to Rfam database...	0.08	0.09	0.07	8	42960	110	10	93	7	78
ASE_00370	RNaseP_bact_a links to Rfam database...	0.03	0.04	0.03	3	41796	109	18	88	3	81
ASE_00372	RNaseP_bact_a links to Rfam database...	0.17	0.20	0.15	20	51871	113	19	93	1	80
ASE_00375	RNaseP_bact_a links to Rfam database...	0.12	0.14	0.11	15	60246	120	10	107	3	95
ASE_00376	RNaseP_bact_a links to Rfam database...	0.00	0.00	0.00	0	56822	136	9	122	5	105
ASE_00386	RNaseP_bact_a links to Rfam database...	0.14	0.16	0.13	15	50284	106	9	95	2	81
ASE_00393	RNaseP_bact_a links to Rfam database...	0.31	0.35	0.27	33	47773	90	18	71	1	60
ASE_00413	RNaseP_bact_a links to Rfam database...	0.08	0.10	0.07	8	44438	108	19	86	3	73
ASE_00416	RNaseP_bact_a links to Rfam database...	0.39	0.43	0.35	54	77267	103	18	82	3	73
ASE_00417	RNaseP_arch links to Rfam database...	0.32	0.36	0.28	36	54486	98	18	75	5	64
ASE_00422	RNaseP_bact_a links to Rfam database...	0.28	0.31	0.25	29	46856	87	9	77	1	65
ASE_00427	RNaseP_nuc links to Rfam database...	0.06	0.09	0.04	4	40651	105	35	65	5	42
ASE_00428	RNaseP_bact_a links to Rfam database...	0.24	0.26	0.22	33	76483	121	13	107	1	92
ASE_00429	-	0.08	0.09	0.07	6	28114	84	14	69	1	60
ASE_00430	RNaseP_bact_a links to Rfam database...	0.16	0.18	0.14	17	46852	102	10	92	0	80
ASE_00434	RNaseP_bact_b links to Rfam database...	0.29	0.34	0.25	37	68116	122	20	92	10	73
ASE_00437	RNaseP_bact_a links to Rfam database...	0.00	0.00	0.00	0	79238	164	12	151	1	135
ASE_00451	RNaseP_bact_a links to Rfam database...	0.20	0.22	0.19	27	70731	118	8	110	0	98
ASE_00454	RNaseP_nuc links to Rfam database...	0.24	0.32	0.19	20	43260	103	28	57	18	43
CRW_00648	-	0.05	0.06	0.04	9	137864	213	24	178	11	139
CRW_00654	-	0.41	0.47	0.36	58	78049	105	18	85	2	66
CRW_00663	-	0.08	0.10	0.07	6	26014	90	17	69	4	55
CRW_00664	-	0.14	0.19	0.11	15	53486	134	42	85	7	63
CRW_00671	Intron_gpI links to Rfam database...	0.18	0.21	0.16	24	62682	130	23	106	1	93
CRW_00672	Intron_gpI links to Rfam database...	0.36	0.43	0.31	48	72233	114	35	74	5	63
CRW_00674	Intron_gpI links to Rfam database...	0.16	0.19	0.14	23	83274	142	19	120	3	101
CRW_00676	Intron_gpI links to Rfam database...	0.11	0.14	0.09	16	93347	169	29	136	4	99
CRW_00685	-	0.11	0.15	0.08	16	156867	212	64	133	15	90
CRW_00721	-	0.22	0.31	0.15	21	58515	133	46	71	16	47
CRW_00756	-	0.04	0.05	0.03	9	194742	253	54	195	4	163
CRW_01539	5S_rRNA links to Rfam database...	0.10	0.11	0.10	4	7099	40	1	36	3	33
CRW_01563	5S_rRNA links to Rfam database...	0.11	0.14	0.11	5	6856	43	5	37	1	32
CRW_01583	5S_rRNA links to Rfam database...	0.36	0.41	0.33	15	7095	31	8	22	1	22
CRW_01590	5S_rRNA links to Rfam database...	-0.01	0.00	0.00	0	7093	50	7	40	3	37
CRW_01603	5S_rRNA links to Rfam database...	0.41	0.46	0.38	17	7095	29	6	22	1	20
PDB_00011	-	0.96	0.92	1.00	11	265	0	0	0	0	1
PDB_00017	-	0.66	0.67	0.67	10	688	5	1	4	0	5
PDB_00036	-	-0.01	0.00	0.00	0	3457	29	1	28	0	27
PDB_00078	-	0.00	0.00	0.00	0	49644	126	10	116	0	115
PDB_00113	-	0.94	0.89	1.00	8	223	0	0	0	0	1
PDB_00119	-	0.95	0.90	1.00	9	244	0	0	0	0	1
PDB_00136	-	0.70	0.73	0.68	19	2387	9	1	8	0	7
PDB_00160	-	0.89	0.89	0.89	8	267	2	0	1	1	1
PDB_00178	-	-0.02	0.00	0.00	0	517	11	1	10	0	11
PDB_00221	-	0.94	0.89	1.00	8	245	0	0	0	0	1
PDB_00278	-	0.04	0.06	0.04	4	24875	98	13	84	1	68
PDB_00312	-	1.00	1.00	1.00	9	426	1	0	0	1	0
PDB_00341	-	0.47	0.44	0.54	7	690	6	0	6	0	9
PDB_00349	-	0.10	0.14	0.10	2	926	18	0	18	0	12
PDB_00417	-	0.00	0.00	0.00	0	14138	58	2	56	0	56
PDB_00527	-	-0.02	0.00	0.00	0	292	8	2	6	0	5
PDB_00565	-	0.24	0.24	0.24	12	8079	37	1	36	0	38
PDB_00570	-	-0.01	0.00	0.00	0	2257	21	0	21	0	22
PDB_00571	tRNA links to Rfam database...	-0.01	0.00	0.00	0	3286	36	6	29	1	25
PDB_00573	-	-0.01	0.00	0.00	0	6622	48	5	43	0	34
PDB_00584	-	0.47	0.53	0.43	9	1464	12	1	11	0	8
PDB_00701	-	0.04	0.05	0.04	5	45319	127	14	113	0	104
PDB_00725	-	0.82	0.80	0.86	12	581	2	0	2	0	3
PDB_00734	-	0.83	0.70	1.00	7	224	0	0	0	0	3
PDB_00823	-	-0.04	0.00	0.00	0	183	7	0	7	0	9
PDB_00828	Purine links to Rfam database...	0.30	0.33	0.28	9	2453	23	0	23	0	18
PDB_00890	-	-0.02	0.00	0.00	0	690	13	2	11	0	14
PDB_00917	-	0.31	0.34	0.29	32	35136	81	10	67	4	63
PDB_01009	tRNA links to Rfam database...	0.27	0.33	0.23	7	2455	25	3	20	2	14
PDB_01051	Telomerase-cil links to Rfam database...	-0.02	0.00	0.00	0	885	18	1	17	0	13
PDB_01074	-	-0.01	0.00	0.00	0	2747	28	3	25	0	25
PDB_01130	-	-0.01	0.00	0.00	0	1742	28	5	23	0	20
PDB_01193	-	0.08	0.09	0.07	14	105834	185	28	154	3	137
PDB_01199	-	-0.01	0.00	0.00	0	2116	29	2	27	0	24
RFA_00416	Hammerhead_3 links to Rfam database...	0.94	1.00	0.88	15	1468	6	2	0	4	0
RFA_00434	Hammerhead_3 links to Rfam database...	0.84	1.00	0.71	15	1410	8	6	0	2	0
RFA_00436	Hammerhead_3 links to Rfam database...	0.86	1.00	0.75	15	1411	7	5	0	2	0
RFA_00442	Hammerhead_3 links to Rfam database...	0.94	1.00	0.88	15	1414	4	2	0	2	0
RFA_00446	Hammerhead_3 links to Rfam database...	0.85	0.93	0.78	14	1467	7	3	1	3	1
RFA_00604	Telomerase-cil links to Rfam database...	0.42	0.54	0.33	19	13472	53	14	25	14	16
RFA_00620	Telomerase-cil links to Rfam database...	0.16	0.23	0.11	9	21864	80	29	43	8	30
RFA_00664	Hammerhead_1 links to Rfam database...	-0.01	0.00	0.00	0	978	13	0	12	1	14
RFA_00674	Hammerhead_1 links to Rfam database...	0.12	0.14	0.13	2	1112	15	0	14	1	12
RFA_00675	Hammerhead_1 links to Rfam database...	0.28	0.29	0.29	4	976	10	1	9	0	10
RFA_00677	Hammerhead_1 links to Rfam database...	0.62	0.64	0.60	9	975	10	0	6	4	5
RFA_00684	Hammerhead_1 links to Rfam database...	0.74	0.71	0.77	10	977	5	2	1	2	4
RFA_00703	Hammerhead_1 links to Rfam database...	0.26	0.36	0.19	5	4252	32	5	16	11	9
RFA_00716	Hammerhead_1 links to Rfam database...	-0.02	0.00	0.00	0	929	17	0	17	0	14
RFA_00717	Hammerhead_1 links to Rfam database...	0.64	0.64	0.64	9	889	5	2	3	0	5
RFA_00730	s2m links to Rfam database...	0.38	0.42	0.36	5	889	10	3	6	1	7
RFA_00763	s2m links to Rfam database...	0.38	0.42	0.36	5	889	10	3	6	1	7
RFA_00765	s2m links to Rfam database...	0.39	0.42	0.38	5	890	9	2	6	1	7
RFA_00770	Corona_pk3 links to Rfam database...	-0.01	0.00	0.00	0	1996	24	0	20	4	18
RFA_00773	Corona_pk3 links to Rfam database...	0.93	1.00	0.86	18	1932	9	3	0	6	0
RFA_00808	RydC links to Rfam database...	0.83	1.00	0.70	16	1993	7	7	0	0	0
RFA_00816	R2_retro_el links to Rfam database...	0.00	0.00	0.00	0	23133	89	30	57	2	41
SPR_00030	-	0.47	0.52	0.42	11	2459	16	2	13	1	10
SPR_00331	tRNA links to Rfam database...	0.48	0.60	0.39	12	2744	19	6	13	0	8
SPR_00333	tRNA links to Rfam database...	0.25	0.33	0.21	7	2741	27	10	17	0	14
SPR_00509	tRNA links to Rfam database...	0.23	0.30	0.19	6	2895	25	8	17	0	14
SPR_00512	tRNA links to Rfam database...	0.61	0.75	0.50	15	2896	15	6	9	0	5
SPR_00557	tRNA links to Rfam database...	0.42	0.52	0.34	11	2818	22	8	13	1	10
SRP_00005	-	-0.01	0.00	0.00	0	3966	39	6	33	0	24
SRP_00038	Bacteria_small_SRP links to Rfam database...	0.23	0.27	0.20	9	5005	36	1	35	0	24
SRP_00117	Metazoa_SRP links to Rfam database...	0.20	0.23	0.18	23	45322	106	9	97	0	79
SRP_00144	Archaea_SRP links to Rfam database...	0.05	0.06	0.05	6	46538	122	17	104	1	88
SRP_00173	Bacteria_large_SRP links to Rfam database...	0.00	0.00	0.00	0	38104	124	13	109	2	90
SRP_00193	-	0.16	0.19	0.15	7	6855	43	4	37	2	29
SRP_00197	Archaea_SRP links to Rfam database...	0.12	0.14	0.11	14	49324	117	16	101	0	87
SRP_00200	Bacteria_small_SRP links to Rfam database...	0.41	0.47	0.35	17	6855	31	4	27	0	19
SRP_00216	Bacteria_small_SRP links to Rfam database...	0.44	0.48	0.41	13	3371	19	4	15	0	14
SRP_00233	Bacteria_small_SRP links to Rfam database...	0.25	0.30	0.22	10	5106	35	4	31	0	23
SRP_00234	Bacteria_large_SRP links to Rfam database...	0.21	0.24	0.18	21	36200	97	19	75	3	65
SRP_00243	Bacteria_small_SRP links to Rfam database...	0.47	0.55	0.40	17	5109	25	7	18	0	14
SRP_00267	Metazoa_SRP links to Rfam database...	0.04	0.05	0.04	5	44424	122	15	107	0	91
SRP_00273	Bacteria_small_SRP links to Rfam database...	0.36	0.40	0.33	16	6737	34	6	27	1	24
SRP_00276	Archaea_SRP links to Rfam database...	0.19	0.22	0.18	24	50585	112	10	102	0	86
SRP_00278	Archaea_SRP links to Rfam database...	0.33	0.36	0.30	38	45928	90	14	76	0	67
SRP_00303	Bacteria_small_SRP links to Rfam database...	0.36	0.41	0.33	13	6630	27	3	24	0	19
SRP_00308	Bacteria_large_SRP links to Rfam database...	0.14	0.17	0.12	15	36189	112	18	93	1	73
SRP_00317	Metazoa_SRP links to Rfam database...	0.14	0.16	0.12	16	45018	116	16	100	0	82
SRP_00321	Archaea_SRP links to Rfam database...	0.44	0.49	0.40	53	47453	81	16	64	1	55
SRP_00322	Archaea_SRP links to Rfam database...	0.22	0.25	0.21	27	48385	105	8	96	1	82
SRP_00332	Archaea_SRP links to Rfam database...	0.12	0.14	0.11	15	50269	120	8	111	1	91
SRP_00337	Bacteria_large_SRP links to Rfam database...	0.42	0.46	0.38	42	35400	70	15	54	1	49
SRP_00338	Bacteria_small_SRP links to Rfam database...	0.52	0.56	0.49	20	5419	22	4	17	1	16
SRP_00342	Bacteria_small_SRP links to Rfam database...	0.20	0.24	0.17	6	3970	29	7	22	0	19
SRP_00354	-	0.06	0.08	0.06	7	38654	120	15	105	0	86
SRP_00355	-	0.09	0.10	0.08	10	41778	119	9	108	2	86
SRP_00383	Bacteria_small_SRP links to Rfam database...	-0.01	0.00	0.00	0	3205	35	9	26	0	24
TMR_00352	tmRNA links to Rfam database...	0.07	0.09	0.05	7	95133	171	39	87	45	68
TMR_00594	tmRNA links to Rfam database...	0.08	0.10	0.06	10	79238	156	30	123	3	94
TMR_00706	tmRNA links to Rfam database...	0.14	0.17	0.11	17	66281	133	29	103	1	86

^top

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.

Table of contents:

Overview

Performance plots

Performance of Afold - scored higher in this pairwise comparison

1. Total counts & total scores for Afold

2. Individual counts for Afold [ download as .csv ]

Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

2. Individual counts for NanoFolder [ download as .csv ]