CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

  4. Performance of HotKnots - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(seed) & HotKnots [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(seed) HotKnots
MCC 0.789 > 0.687
Average MCC ± 95% Confidence Intervals 0.775 ± 0.028 > 0.663 ± 0.041
Sensitivity 0.698 > 0.688
Positive Predictive Value 0.895 > 0.691
Total TP 3486 > 3437
Total TN 806152 > 805073
Total FP 744 < 1928
Total FP CONTRA 59 < 236
Total FP INCONS 352 < 1303
Total FP COMP 333 < 389
Total FN 1510 < 1559
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of CentroidAlifold(seed) and HotKnots. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(seed) and HotKnots).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for CentroidAlifold(seed) and HotKnots).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(seed) and HotKnots. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(seed) and HotKnots).

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Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP 3486
Total TN 806152
Total FP 744
Total FP CONTRA 59
Total FP INCONS 352
Total FP COMP 333
Total FN 1510
Total Scores
MCC 0.789
Average MCC ± 95% Confidence Intervals 0.775 ± 0.028
Sensitivity 0.698
Positive Predictive Value 0.895
Nr of predictions 213

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2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
PDB_00005 0.80 0.64 1.00 9 937 0 0 0 0 5
PDB_00012 1.00 1.00 1.00 7 399 2 0 0 2 0
PDB_00213 0.85 0.73 1.00 30 5020 0 0 0 0 11
PDB_00553 0.95 0.91 1.00 10 455 0 0 0 0 1
PDB_00716 0.75 0.61 0.93 14 2686 1 0 1 0 9
PDB_00741 0.72 0.53 1.00 9 694 0 0 0 0 8
PDB_00810 0.87 0.76 1.00 13 1068 1 0 0 1 4
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.91 0.83 1.00 20 2258 0 0 0 0 4
PDB_00876 0.53 0.50 0.59 10 973 7 0 7 0 10
PDB_01001 0.00 0.00 0.00 0 2139 6 0 6 0 18
PDB_01020 0.91 0.83 1.00 19 2259 1 0 0 1 4
PDB_01050 0.68 0.46 1.00 6 624 2 0 0 2 7
PDB_01051 0.96 0.92 1.00 12 891 4 0 0 4 1
PDB_01073 0.84 0.71 1.00 24 4347 1 0 0 1 10
PDB_01092 0.72 0.58 0.91 30 10120 4 0 3 1 22
PDB_01114 0.77 0.59 1.00 16 2834 1 0 0 1 11
PDB_01152 0.80 0.64 1.00 9 552 0 0 0 0 5
PDB_01236 0.88 0.78 1.00 42 11586 3 0 0 3 12
RFA_00389 0.97 0.93 1.00 14 1417 3 0 0 3 1
RFA_00390 0.97 0.93 1.00 14 1417 2 0 0 2 1
RFA_00391 0.97 0.93 1.00 14 1417 3 0 0 3 1
RFA_00396 0.97 0.93 1.00 14 1417 3 0 0 3 1
RFA_00402 0.97 0.93 1.00 14 1417 3 0 0 3 1
RFA_00409 0.97 0.93 1.00 14 1417 3 0 0 3 1
RFA_00416 0.97 0.93 1.00 14 1471 2 0 0 2 1
RFA_00425 0.97 0.93 1.00 14 1639 3 0 0 3 1
RFA_00427 0.97 0.93 1.00 14 1471 3 0 0 3 1
RFA_00433 0.97 0.93 1.00 14 1417 2 0 0 2 1
RFA_00434 0.97 0.93 1.00 14 1417 3 0 0 3 1
RFA_00436 0.97 0.93 1.00 14 1417 3 0 0 3 1
RFA_00440 0.97 0.93 1.00 14 1471 3 0 0 3 1
RFA_00442 0.97 0.93 1.00 14 1417 3 0 0 3 1
RFA_00444 0.97 0.93 1.00 14 1526 3 0 0 3 1
RFA_00446 0.97 0.93 1.00 14 1471 3 0 0 3 1
RFA_00449 0.97 0.93 1.00 14 1471 3 0 0 3 1
RFA_00582 1.00 1.00 1.00 15 5980 3 0 0 3 0
RFA_00583 1.00 1.00 1.00 15 4935 3 0 0 3 0
RFA_00584 1.00 1.00 1.00 15 2911 3 0 0 3 0
RFA_00585 1.00 1.00 1.00 15 4836 3 0 0 3 0
RFA_00586 1.00 1.00 1.00 15 3901 3 0 0 3 0
RFA_00587 1.00 1.00 1.00 15 4836 3 0 0 3 0
RFA_00588 1.00 1.00 1.00 15 4545 3 0 0 3 0
RFA_00589 0.97 0.93 1.00 14 4357 3 0 0 3 1
RFA_00594 1.00 1.00 1.00 15 2760 3 0 0 3 0
RFA_00596 0.93 0.87 1.00 13 5982 3 0 0 3 2
RFA_00603 0.96 0.91 1.00 32 13498 0 0 0 0 3
RFA_00604 0.97 0.94 1.00 33 13497 0 0 0 0 2
RFA_00605 0.97 0.94 1.00 33 15192 0 0 0 0 2
RFA_00611 0.96 0.91 1.00 32 13009 0 0 0 0 3
RFA_00613 0.97 0.94 1.00 33 12847 0 0 0 0 2
RFA_00615 0.85 0.80 0.90 28 13335 3 0 3 0 7
RFA_00620 0.91 0.82 1.00 32 21913 0 0 0 0 7
RFA_00632 0.74 0.64 0.86 18 4074 3 2 1 0 10
RFA_00636 0.78 0.68 0.90 19 3984 2 2 0 0 9
RFA_00642 0.41 0.17 1.00 3 2923 0 0 0 0 15
RFA_00643 0.00 0.00 0.00 0 2211 0 0 0 0 18
RFA_00644 0.00 0.00 0.00 0 2701 0 0 0 0 18
RFA_00645 0.23 0.06 1.00 1 2414 0 0 0 0 17
RFA_00649 0.00 0.00 0.00 0 2145 0 0 0 0 18
RFA_00651 0.00 0.00 0.00 0 2080 0 0 0 0 18
RFA_00653 0.33 0.11 1.00 2 2143 0 0 0 0 16
RFA_00654 0.00 0.00 0.00 0 2415 0 0 0 0 18
RFA_00658 0.71 0.57 0.89 8 1119 2 0 1 1 6
RFA_00659 0.65 0.43 1.00 6 1122 0 0 0 0 8
RFA_00664 0.65 0.43 1.00 6 984 0 0 0 0 8
RFA_00667 0.65 0.43 1.00 6 984 0 0 0 0 8
RFA_00668 0.65 0.43 1.00 6 984 0 0 0 0 8
RFA_00672 0.78 0.62 1.00 8 895 0 0 0 0 5
RFA_00673 0.65 0.43 1.00 6 1122 0 0 0 0 8
RFA_00674 0.60 0.43 0.86 6 1121 1 0 1 0 8
RFA_00675 0.65 0.43 1.00 6 984 0 0 0 0 8
RFA_00677 0.65 0.43 1.00 6 984 0 0 0 0 8
RFA_00678 0.65 0.43 1.00 6 940 0 0 0 0 8
RFA_00680 0.65 0.43 1.00 6 1122 0 0 0 0 8
RFA_00684 0.65 0.43 1.00 6 984 0 0 0 0 8
RFA_00685 0.65 0.43 1.00 6 984 0 0 0 0 8
RFA_00695 0.80 0.64 1.00 9 7012 0 0 0 0 5
RFA_00703 0.80 0.64 1.00 9 4269 0 0 0 0 5
RFA_00704 0.65 0.43 1.00 6 984 0 0 0 0 8
RFA_00705 0.76 0.64 0.90 9 1025 2 0 1 1 5
RFA_00706 0.65 0.43 1.00 6 1029 0 0 0 0 8
RFA_00707 0.65 0.43 1.00 6 1029 0 0 0 0 8
RFA_00708 0.71 0.57 0.89 8 1026 2 0 1 1 6
RFA_00709 0.65 0.43 1.00 6 984 0 0 0 0 8
RFA_00710 0.72 0.64 0.82 9 979 3 0 2 1 5
RFA_00711 0.65 0.43 1.00 6 1029 0 0 0 0 8
RFA_00715 0.65 0.43 1.00 6 940 0 0 0 0 8
RFA_00716 0.65 0.43 1.00 6 940 0 0 0 0 8
RFA_00717 0.75 0.57 1.00 8 895 0 0 0 0 6
RFA_00730 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00731 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00733 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00734 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00736 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00737 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00745 1.00 1.00 1.00 12 934 2 0 0 2 0
RFA_00749 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00758 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00762 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00763 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00764 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00765 1.00 1.00 1.00 12 891 2 0 0 2 0
RFA_00767 0.74 0.56 1.00 10 1881 0 0 0 0 8
RFA_00768 0.74 0.56 1.00 10 1881 0 0 0 0 8
RFA_00769 0.74 0.56 1.00 10 1943 0 0 0 0 8
RFA_00770 0.74 0.56 1.00 10 2006 0 0 0 0 8
RFA_00773 0.74 0.56 1.00 10 1943 0 0 0 0 8
RFA_00779 0.74 0.56 1.00 10 1943 0 0 0 0 8
RFA_00781 0.97 0.94 1.00 30 5020 0 0 0 0 2
RFA_00786 0.97 0.94 1.00 30 5020 0 0 0 0 2
RFA_00791 0.97 0.94 1.00 30 5121 0 0 0 0 2
RFA_00792 0.97 0.94 1.00 30 5020 0 0 0 0 2
RFA_00801 0.97 0.94 1.00 30 5020 0 0 0 0 2
RFA_00808 0.65 0.56 0.75 9 2004 3 1 2 0 7
RFA_00809 0.43 0.38 0.50 6 2133 6 0 6 0 10
SPR_00020 0.55 0.30 1.00 6 2695 0 0 0 0 14
SPR_00023 0.53 0.29 1.00 6 2844 0 0 0 0 15
SPR_00137 0.49 0.24 1.00 5 2921 1 0 0 1 16
SPR_00273 0.44 0.24 0.83 5 2844 1 0 1 0 16
SPR_00277 0.53 0.29 1.00 6 2920 0 0 0 0 15
SPR_00394 0.53 0.29 1.00 6 3649 0 0 0 0 15
SPR_00402 0.53 0.29 1.00 6 2550 0 0 0 0 15
SPR_00721 0.53 0.29 1.00 6 2920 0 0 0 0 15
SPR_00816 0.55 0.30 1.00 6 3480 0 0 0 0 14
SPR_01157 0.53 0.29 1.00 6 2769 0 0 0 0 15
SRP_00001 0.82 0.68 1.00 27 6759 5 0 0 5 13
SRP_00008 0.96 0.92 1.00 23 2903 2 0 0 2 2
SRP_00020 0.89 0.85 0.93 28 5535 2 1 1 0 5
SRP_00038 0.90 0.82 1.00 27 5023 3 0 0 3 6
SRP_00040 0.55 0.52 0.59 16 5538 14 1 10 3 15
SRP_00042 0.85 0.80 0.91 20 3983 6 1 1 4 5
SRP_00043 0.42 0.41 0.43 12 5022 18 2 14 2 17
SRP_00044 0.85 0.81 0.90 26 6076 4 1 2 1 6
SRP_00046 0.94 0.88 1.00 28 4725 2 0 0 2 4
SRP_00051 0.76 0.67 0.87 20 5437 7 0 3 4 10
SRP_00054 0.92 0.84 1.00 27 5538 3 0 0 3 5
SRP_00056 0.63 0.54 0.74 20 6414 9 1 6 2 17
SRP_00057 0.79 0.69 0.92 24 6302 6 1 1 4 11
SRP_00058 0.88 0.82 0.93 28 5748 2 1 1 0 6
SRP_00067 0.81 0.71 0.93 27 5749 3 1 1 1 11
SRP_00072 0.68 0.66 0.70 19 6301 11 0 8 3 10
SRP_00074 0.52 0.48 0.56 14 6530 16 0 11 5 15
SRP_00075 0.34 0.32 0.37 11 5535 19 0 19 0 23
SRP_00077 0.59 0.51 0.68 19 6642 11 0 9 2 18
SRP_00081 0.65 0.65 0.67 20 5535 10 1 9 0 11
SRP_00084 0.88 0.82 0.93 28 5430 2 1 1 0 6
SRP_00094 0.82 0.83 0.80 20 4070 9 1 4 4 4
SRP_00095 0.82 0.84 0.81 21 3979 8 1 4 3 4
SRP_00098 0.65 0.57 0.75 21 6413 9 1 6 2 16
SRP_00105 0.89 0.79 1.00 27 5538 3 0 0 3 7
SRP_00106 0.69 0.72 0.67 18 5226 15 3 6 6 7
SRP_00107 0.46 0.53 0.40 10 3630 19 3 12 4 9
SRP_00121 0.82 0.80 0.83 20 4254 6 0 4 2 5
SRP_00128 0.82 0.72 0.93 26 6758 4 1 1 2 10
SRP_00132 0.73 0.69 0.77 20 4825 9 0 6 3 9
SRP_00134 0.70 0.62 0.78 18 5972 13 0 5 8 11
SRP_00137 0.66 0.68 0.65 17 4160 10 3 6 1 8
SRP_00141 0.78 0.66 0.93 27 6299 3 1 1 1 14
SRP_00145 0.81 0.70 0.93 28 6298 2 1 1 0 12
SRP_00146 0.83 0.75 0.93 27 5224 3 1 1 1 9
SRP_00161 0.84 0.82 0.86 18 2829 5 0 3 2 4
SRP_00162 0.87 0.87 0.87 20 2903 4 0 3 1 3
SRP_00163 0.84 0.81 0.88 21 3462 5 0 3 2 5
SRP_00164 0.78 0.66 0.92 23 6878 7 1 1 5 12
SRP_00170 0.83 0.76 0.90 19 4074 6 1 1 4 6
SRP_00194 0.71 0.71 0.71 15 3219 9 0 6 3 6
SRP_00200 0.77 0.67 0.89 24 6876 6 1 2 3 12
SRP_00209 0.75 0.74 0.77 20 4630 9 1 5 3 7
SRP_00213 0.92 0.92 0.92 23 4161 6 1 1 4 2
SRP_00215 0.86 0.84 0.88 21 3216 4 0 3 1 4
SRP_00216 0.93 0.93 0.93 25 3376 4 1 1 2 2
SRP_00217 0.89 0.88 0.91 21 3298 4 0 2 2 3
SRP_00219 0.89 0.87 0.91 20 3299 5 0 2 3 3
SRP_00222 0.87 0.84 0.91 21 3058 3 1 1 1 4
SRP_00227 0.86 0.81 0.93 25 5124 5 1 1 3 6
SRP_00229 0.41 0.41 0.42 11 5227 19 0 15 4 16
SRP_00231 0.88 0.82 0.93 28 5430 2 1 1 0 6
SRP_00233 0.87 0.82 0.93 27 5122 3 0 2 1 6
SRP_00243 0.88 0.81 0.96 25 5125 5 0 1 4 6
SRP_00244 0.74 0.62 0.89 24 6876 5 1 2 2 15
SRP_00250 0.67 0.58 0.78 21 6759 9 1 5 3 15
SRP_00251 0.77 0.67 0.89 24 6994 6 1 2 3 12
SRP_00266 0.55 0.55 0.55 16 4627 14 2 11 1 13
SRP_00268 0.91 0.89 0.92 24 4160 5 1 1 3 3
SRP_00269 0.68 0.64 0.72 21 5021 9 0 8 1 12
SRP_00270 0.86 0.81 0.93 25 4629 5 0 2 3 6
SRP_00271 0.89 0.88 0.91 21 3217 3 0 2 1 3
SRP_00273 0.79 0.68 0.93 27 6757 3 1 1 1 13
SRP_00274 0.81 0.71 0.93 27 6874 3 1 1 1 11
SRP_00285 0.87 0.77 1.00 23 3718 2 0 0 2 7
SRP_00295 0.78 0.66 0.93 25 6876 5 1 1 3 13
SRP_00303 0.68 0.63 0.74 20 6643 10 1 6 3 12
SRP_00310 0.82 0.83 0.83 19 2903 5 0 4 1 4
SRP_00312 0.91 0.89 0.92 24 4160 5 1 1 3 3
SRP_00315 0.81 0.83 0.79 19 2902 5 0 5 0 4
SRP_00318 0.81 0.83 0.79 19 2979 5 0 5 0 4
SRP_00324 0.62 0.59 0.65 17 5330 10 1 8 1 12
SRP_00325 0.87 0.82 0.93 27 4342 3 0 2 1 6
SRP_00326 0.86 0.81 0.93 25 5023 5 0 2 3 6
SRP_00333 0.86 0.79 0.93 27 5122 3 0 2 1 7
SRP_00338 0.90 0.81 1.00 29 5431 1 0 0 1 7
SRP_00341 0.44 0.42 0.46 13 4725 17 0 15 2 18
SRP_00342 0.72 0.72 0.72 18 3980 12 0 7 5 7
SRP_00350 0.84 0.78 0.91 21 3893 4 1 1 2 6
SRP_00356 0.80 0.73 0.88 22 5025 6 0 3 3 8
SRP_00357 0.82 0.72 0.93 26 5328 4 1 1 2 10
SRP_00358 0.81 0.71 0.93 25 6301 5 1 1 3 10
SRP_00363 0.82 0.77 0.88 23 4727 7 0 3 4 7
SRP_00365 0.84 0.78 0.91 21 3380 4 0 2 2 6
SRP_00367 0.79 0.69 0.92 24 6760 6 1 1 4 11
SRP_00369 0.78 0.66 0.92 23 5753 7 1 1 5 12
SRP_00383 0.92 0.92 0.92 22 3216 6 0 2 4 2

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Performance of HotKnots - scored lower in this pairwise comparison

1. Total counts & total scores for HotKnots

Total Base Pair Counts
Total TP 3437
Total TN 805073
Total FP 1928
Total FP CONTRA 236
Total FP INCONS 1303
Total FP COMP 389
Total FN 1559
Total Scores
MCC 0.687
Average MCC ± 95% Confidence Intervals 0.663 ± 0.041
Sensitivity 0.688
Positive Predictive Value 0.691
Nr of predictions 213

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2. Individual counts for HotKnots [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
PDB_00005 0.88 0.79 1.00 11 935 0 0 0 0 3
PDB_00012 1.00 1.00 1.00 7 399 3 0 0 3 0
PDB_00213 0.92 0.85 1.00 35 5015 0 0 0 0 6
PDB_00553 1.00 1.00 1.00 11 454 0 0 0 0 0
PDB_00716 -0.01 0.00 0.00 0 2678 24 1 22 1 23
PDB_00741 0.87 0.76 1.00 13 690 0 0 0 0 4
PDB_00810 0.71 0.65 0.79 11 1067 4 0 3 1 6
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.86 0.75 1.00 18 2260 0 0 0 0 6
PDB_00876 0.97 0.95 1.00 19 971 0 0 0 0 1
PDB_01001 0.52 0.56 0.50 10 2125 10 3 7 0 8
PDB_01020 0.86 0.74 1.00 17 2261 1 0 0 1 6
PDB_01050 0.96 0.92 1.00 12 618 2 0 0 2 1
PDB_01051 0.75 0.69 0.82 9 892 6 0 2 4 4
PDB_01073 0.81 0.74 0.89 25 4343 4 2 1 1 9
PDB_01092 0.69 0.65 0.74 34 10107 13 0 12 1 18
PDB_01114 0.58 0.52 0.67 14 2829 7 0 7 0 13
PDB_01152 0.92 0.86 1.00 12 549 0 0 0 0 2
PDB_01236 0.61 0.57 0.65 31 11580 20 0 17 3 23
RFA_00389 1.00 1.00 1.00 15 1416 2 0 0 2 0
RFA_00390 1.00 1.00 1.00 15 1416 2 0 0 2 0
RFA_00391 0.93 0.87 1.00 13 1418 2 0 0 2 2
RFA_00396 0.97 0.93 1.00 14 1417 2 0 0 2 1
RFA_00402 1.00 1.00 1.00 15 1416 0 0 0 0 0
RFA_00409 0.55 0.53 0.57 8 1417 7 1 5 1 7
RFA_00416 0.93 0.93 0.93 14 1470 4 0 1 3 1
RFA_00425 0.93 0.87 1.00 13 1640 4 0 0 4 2
RFA_00427 0.97 0.93 1.00 14 1471 2 0 0 2 1
RFA_00433 1.00 1.00 1.00 15 1416 2 0 0 2 0
RFA_00434 1.00 1.00 1.00 15 1416 2 0 0 2 0
RFA_00436 1.00 1.00 1.00 15 1416 2 0 0 2 0
RFA_00440 1.00 1.00 1.00 15 1470 2 0 0 2 0
RFA_00442 1.00 1.00 1.00 15 1416 2 0 0 2 0
RFA_00444 1.00 1.00 1.00 15 1525 1 0 0 1 0
RFA_00446 0.97 0.93 1.00 14 1471 2 0 0 2 1
RFA_00449 0.97 0.93 1.00 14 1471 2 0 0 2 1
RFA_00582 1.00 1.00 1.00 15 5980 21 0 0 21 0
RFA_00583 0.55 0.53 0.57 8 4936 20 0 6 14 7
RFA_00584 0.87 0.87 0.87 13 2911 14 0 2 12 2
RFA_00585 1.00 1.00 1.00 15 4836 13 0 0 13 0
RFA_00586 0.89 0.80 1.00 12 3904 11 0 0 11 3
RFA_00587 1.00 1.00 1.00 15 4836 12 0 0 12 0
RFA_00588 0.93 0.87 1.00 13 4547 12 0 0 12 2
RFA_00589 0.93 0.87 1.00 13 4358 16 0 0 16 2
RFA_00594 0.97 0.93 1.00 14 2761 11 0 0 11 1
RFA_00596 0.00 0.00 0.00 0 5981 23 4 10 9 15
RFA_00603 0.64 0.69 0.60 24 13490 19 4 12 3 11
RFA_00604 0.72 0.74 0.70 26 13493 22 2 9 11 9
RFA_00605 0.37 0.34 0.40 12 15195 27 3 15 9 23
RFA_00611 0.63 0.63 0.63 22 13006 15 3 10 2 13
RFA_00613 0.61 0.60 0.62 21 12846 15 4 9 2 14
RFA_00615 0.51 0.51 0.51 18 13331 17 8 9 0 17
RFA_00620 0.64 0.62 0.67 24 21909 25 3 9 13 15
RFA_00632 0.38 0.39 0.37 11 4065 19 2 17 0 17
RFA_00636 0.42 0.43 0.43 12 3977 16 2 14 0 16
RFA_00642 0.16 0.17 0.17 3 2908 15 1 14 0 15
RFA_00643 0.20 0.22 0.20 4 2191 16 1 15 0 14
RFA_00644 -0.01 0.00 0.00 0 2676 25 6 19 0 18
RFA_00645 -0.01 0.00 0.00 0 2394 21 4 17 0 18
RFA_00649 0.34 0.33 0.35 6 2128 13 2 9 2 12
RFA_00651 0.35 0.33 0.38 6 2064 10 1 9 0 12
RFA_00653 0.34 0.33 0.35 6 2128 11 3 8 0 12
RFA_00654 0.27 0.28 0.28 5 2397 13 2 11 0 13
RFA_00658 0.59 0.50 0.70 7 1118 5 0 3 2 7
RFA_00659 -0.01 0.00 0.00 0 1120 10 1 7 2 14
RFA_00664 -0.01 0.00 0.00 0 980 11 0 10 1 14
RFA_00667 0.30 0.29 0.33 4 978 8 1 7 0 10
RFA_00668 0.41 0.43 0.40 6 975 9 0 9 0 8
RFA_00672 -0.01 0.00 0.00 0 895 9 0 8 1 13
RFA_00673 0.42 0.36 0.50 5 1118 6 0 5 1 9
RFA_00674 0.71 0.71 0.71 10 1114 5 0 4 1 4
RFA_00675 0.29 0.29 0.31 4 977 9 1 8 0 10
RFA_00677 0.42 0.43 0.43 6 976 9 0 8 1 8
RFA_00678 0.43 0.29 0.67 4 940 2 0 2 0 10
RFA_00680 0.74 0.71 0.77 10 1115 6 0 3 3 4
RFA_00684 0.66 0.64 0.69 9 977 5 0 4 1 5
RFA_00685 0.42 0.36 0.50 5 980 6 0 5 1 9
RFA_00695 0.56 0.50 0.64 7 7010 29 1 3 25 7
RFA_00703 0.67 0.64 0.69 9 4265 18 1 3 14 5
RFA_00704 -0.01 0.00 0.00 0 976 14 2 12 0 14
RFA_00705 0.69 0.71 0.67 10 1020 5 0 5 0 4
RFA_00706 0.29 0.29 0.31 4 1022 10 0 9 1 10
RFA_00707 -0.01 0.00 0.00 0 1026 9 3 6 0 14
RFA_00708 0.30 0.29 0.33 4 1023 10 0 8 2 10
RFA_00709 -0.01 0.00 0.00 0 981 10 0 9 1 14
RFA_00710 -0.01 0.00 0.00 0 981 9 0 9 0 14
RFA_00711 -0.01 0.00 0.00 0 1026 10 0 9 1 14
RFA_00715 -0.01 0.00 0.00 0 936 10 0 10 0 14
RFA_00716 -0.01 0.00 0.00 0 935 11 0 11 0 14
RFA_00717 0.64 0.64 0.64 9 889 5 0 5 0 5
RFA_00730 0.69 0.67 0.73 8 892 4 1 2 1 4
RFA_00731 0.66 0.67 0.67 8 891 5 1 3 1 4
RFA_00733 0.66 0.67 0.67 8 891 5 1 3 1 4
RFA_00734 0.61 0.67 0.57 8 889 7 1 5 1 4
RFA_00736 0.66 0.67 0.67 8 891 5 1 3 1 4
RFA_00737 0.75 0.75 0.75 9 891 5 0 3 2 3
RFA_00745 0.66 0.67 0.67 8 934 5 1 3 1 4
RFA_00749 0.66 0.67 0.67 8 891 5 1 3 1 4
RFA_00758 0.63 0.58 0.70 7 893 3 1 2 0 5
RFA_00762 0.64 0.67 0.62 8 890 5 1 4 0 4
RFA_00763 0.75 0.75 0.75 9 891 4 0 3 1 3
RFA_00764 0.66 0.67 0.67 8 891 5 1 3 1 4
RFA_00765 0.75 0.75 0.75 9 891 5 0 3 2 3
RFA_00767 0.93 1.00 0.86 18 1870 3 3 0 0 0
RFA_00768 1.00 1.00 1.00 18 1873 0 0 0 0 0
RFA_00769 -0.01 0.00 0.00 0 1934 21 0 19 2 18
RFA_00770 -0.01 0.00 0.00 0 1999 20 0 17 3 18
RFA_00773 -0.01 0.00 0.00 0 1934 22 0 19 3 18
RFA_00779 0.87 0.94 0.81 17 1932 4 3 1 0 1
RFA_00781 0.58 0.59 0.58 19 5017 14 2 12 0 13
RFA_00786 0.71 0.72 0.70 23 5017 10 2 8 0 9
RFA_00791 0.35 0.34 0.35 11 5120 20 5 15 0 21
RFA_00792 0.94 0.94 0.94 30 5018 4 0 2 2 2
RFA_00801 0.85 0.81 0.90 26 5021 4 0 3 1 6
RFA_00808 1.00 1.00 1.00 16 2000 0 0 0 0 0
RFA_00809 0.79 0.81 0.76 13 2128 4 0 4 0 3
SPR_00020 0.76 0.80 0.73 16 2679 8 2 4 2 4
SPR_00023 0.49 0.52 0.46 11 2826 13 3 10 0 10
SPR_00137 0.56 0.62 0.52 13 2901 15 4 8 3 8
SPR_00273 0.30 0.33 0.28 7 2825 18 2 16 0 14
SPR_00277 0.98 0.95 1.00 20 2906 0 0 0 0 1
SPR_00394 0.30 0.33 0.28 7 3630 20 8 10 2 14
SPR_00402 0.67 0.62 0.72 13 2538 5 0 5 0 8
SPR_00721 0.48 0.52 0.44 11 2901 14 3 11 0 10
SPR_00816 0.31 0.35 0.28 7 3461 21 5 13 3 13
SPR_01157 0.54 0.57 0.52 12 2752 12 0 11 1 9
SRP_00001 0.94 0.95 0.93 38 6745 3 1 2 0 2
SRP_00008 0.70 0.72 0.69 18 2900 9 0 8 1 7
SRP_00020 0.86 0.88 0.85 29 5531 5 1 4 0 4
SRP_00038 0.94 0.94 0.94 31 5017 2 0 2 0 2
SRP_00040 0.70 0.74 0.66 23 5530 14 1 11 2 8
SRP_00042 0.46 0.48 0.44 12 3978 17 1 14 2 13
SRP_00043 0.45 0.48 0.42 14 5017 22 4 15 3 15
SRP_00044 0.77 0.75 0.80 24 6075 7 1 5 1 8
SRP_00046 0.97 0.97 0.97 31 4721 2 0 1 1 1
SRP_00051 0.97 0.97 0.97 29 5430 3 0 1 2 1
SRP_00054 0.45 0.44 0.47 14 5535 16 0 16 0 18
SRP_00056 0.84 0.84 0.84 31 6404 6 1 5 0 6
SRP_00057 0.69 0.69 0.71 24 6294 11 2 8 1 11
SRP_00058 0.90 0.91 0.89 31 5743 8 1 3 4 3
SRP_00067 0.96 0.97 0.95 37 5739 2 1 1 0 1
SRP_00072 1.00 1.00 1.00 29 6299 1 0 0 1 0
SRP_00074 0.39 0.41 0.36 12 6522 25 3 18 4 17
SRP_00075 0.82 0.79 0.84 27 5533 8 0 5 3 7
SRP_00077 0.21 0.22 0.21 8 6631 31 4 27 0 29
SRP_00081 0.68 0.74 0.62 23 5528 14 1 13 0 8
SRP_00084 0.87 0.88 0.86 30 5425 5 1 4 0 4
SRP_00094 0.86 0.88 0.84 21 4070 4 0 4 0 3
SRP_00095 0.81 0.84 0.78 21 3978 6 1 5 0 4
SRP_00098 0.72 0.73 0.71 27 6403 12 1 10 1 10
SRP_00105 0.38 0.38 0.39 13 5532 20 3 17 0 21
SRP_00106 0.67 0.76 0.59 19 5221 16 5 8 3 6
SRP_00107 0.13 0.16 0.11 3 3628 26 6 18 2 16
SRP_00121 0.80 0.80 0.80 20 4253 6 0 5 1 5
SRP_00128 0.76 0.81 0.73 29 6746 12 1 10 1 7
SRP_00132 0.65 0.69 0.63 20 4819 15 0 12 3 9
SRP_00134 0.51 0.55 0.48 16 5962 23 3 14 6 13
SRP_00137 0.74 0.84 0.66 21 4154 13 4 7 2 4
SRP_00141 0.91 0.90 0.93 37 6288 3 1 2 0 4
SRP_00145 0.96 0.98 0.95 39 6287 2 1 1 0 1
SRP_00146 0.93 0.94 0.92 34 5216 3 1 2 0 2
SRP_00161 0.89 0.91 0.87 20 2827 3 0 3 0 2
SRP_00162 0.89 0.91 0.88 21 2902 4 0 3 1 2
SRP_00163 0.76 0.81 0.72 21 3457 8 2 6 0 5
SRP_00164 0.96 0.97 0.94 34 6867 3 1 1 1 1
SRP_00170 0.55 0.56 0.54 14 4069 13 0 12 1 11
SRP_00194 0.77 0.81 0.74 17 3217 6 0 6 0 4
SRP_00200 0.92 0.94 0.89 34 6865 4 1 3 0 2
SRP_00209 0.80 0.81 0.79 22 4628 6 0 6 0 5
SRP_00213 0.35 0.40 0.31 10 4154 22 5 17 0 15
SRP_00215 0.82 0.80 0.83 20 3216 4 0 4 0 5
SRP_00216 0.93 0.93 0.93 25 3376 3 1 1 1 2
SRP_00217 0.94 0.96 0.92 23 3296 3 0 2 1 1
SRP_00219 0.94 0.96 0.92 22 3297 3 0 2 1 1
SRP_00222 0.94 0.96 0.92 24 3055 3 1 1 1 1
SRP_00227 0.95 0.97 0.94 30 5119 2 1 1 0 1
SRP_00229 0.43 0.44 0.41 12 5224 17 5 12 0 15
SRP_00231 0.87 0.88 0.86 30 5425 5 1 4 0 4
SRP_00233 0.97 0.94 1.00 31 5120 0 0 0 0 2
SRP_00243 0.97 0.94 1.00 29 5122 1 0 0 1 2
SRP_00244 0.92 0.90 0.95 35 6866 3 1 1 1 4
SRP_00250 0.74 0.75 0.73 27 6749 13 1 9 3 9
SRP_00251 0.70 0.72 0.68 26 6983 12 1 11 0 10
SRP_00266 0.71 0.72 0.70 21 4626 10 1 8 1 8
SRP_00268 0.47 0.48 0.46 13 4158 15 4 11 0 14
SRP_00269 0.59 0.61 0.57 20 5015 15 3 12 0 13
SRP_00270 0.42 0.45 0.40 14 4621 21 2 19 0 17
SRP_00271 -0.01 0.00 0.00 0 3215 25 3 22 0 24
SRP_00273 0.91 0.93 0.90 37 6745 6 1 3 2 3
SRP_00274 0.96 0.97 0.95 37 6864 3 1 1 1 1
SRP_00285 0.91 0.87 0.96 26 3714 1 0 1 0 4
SRP_00295 0.93 0.92 0.95 35 6866 5 1 1 3 3
SRP_00303 0.69 0.72 0.66 23 6635 12 1 11 0 9
SRP_00310 0.89 0.91 0.88 21 2902 4 0 3 1 2
SRP_00312 0.36 0.37 0.36 10 4158 18 4 14 0 17
SRP_00315 0.87 0.87 0.87 20 2903 3 0 3 0 3
SRP_00318 0.87 0.87 0.87 20 2980 3 0 3 0 3
SRP_00324 0.57 0.62 0.53 18 5322 16 5 11 0 11
SRP_00325 1.00 1.00 1.00 33 4338 0 0 0 0 0
SRP_00326 0.55 0.55 0.55 17 5019 14 3 11 0 14
SRP_00333 0.86 0.85 0.88 29 5118 4 0 4 0 5
SRP_00338 0.94 0.94 0.94 34 5424 2 0 2 0 2
SRP_00341 0.74 0.74 0.74 23 4722 8 0 8 0 8
SRP_00342 0.55 0.56 0.54 14 3979 17 1 11 5 11
SRP_00350 0.34 0.33 0.35 9 3890 17 2 15 0 18
SRP_00356 0.65 0.67 0.65 20 5019 11 2 9 0 10
SRP_00357 0.93 0.92 0.94 33 5321 3 1 1 1 3
SRP_00358 0.93 0.91 0.94 32 6294 3 1 1 1 3
SRP_00363 0.95 0.97 0.94 29 4722 4 0 2 2 1
SRP_00365 0.91 0.89 0.92 24 3377 2 0 2 0 3
SRP_00367 0.96 0.97 0.94 34 6750 2 1 1 0 1
SRP_00369 0.93 0.91 0.94 32 5744 2 1 1 0 3
SRP_00383 0.12 0.13 0.13 3 3216 21 3 18 0 21

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.