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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(20) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(20) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric Murlet(20) Multilign(seed)
MCC 0.568 > 0.334
Average MCC ± 95% Confidence Intervals 0.322 ± 1.385 > 0.190 ± 0.816
Sensitivity 0.326 > 0.186
Positive Predictive Value 1.000 > 0.615
Total TP 14 > 8
Total TN 3589 < 3590
Total FP 2 < 6
Total FP CONTRA 0 < 1
Total FP INCONS 0 < 4
Total FP COMP 2 > 1
Total FN 29 < 35
P-value 0.0

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Performance plots


  1. Comparison of performance of Murlet(20) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(20) and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(20) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(20) and Multilign(seed)).

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Performance of Murlet(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 14
Total TN 3589
Total FP 2
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 2
Total FN 29
Total Scores
MCC 0.568
Average MCC ± 95% Confidence Intervals 0.322 ± 1.385
Sensitivity 0.326
Positive Predictive Value 1.000
Nr of predictions 3

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00416 0.97 0.93 1.00 14 1471 2 0 0 2 1
RFA_00658 0.00 0.00 0.00 0 1128 0 0 0 0 14
RFA_00664 0.00 0.00 0.00 0 990 0 0 0 0 14

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 8
Total TN 3590
Total FP 6
Total FP CONTRA 1
Total FP INCONS 4
Total FP COMP 1
Total FN 35
Total Scores
MCC 0.334
Average MCC ± 95% Confidence Intervals 0.190 ± 0.816
Sensitivity 0.186
Positive Predictive Value 0.615
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00416 0.57 0.53 0.62 8 1472 6 1 4 1 7
RFA_00658 0.00 0.00 0.00 0 1128 0 0 0 0 14
RFA_00664 0.00 0.00 0.00 0 990 0 0 0 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.