CompaRNA - on-line benchmarks of RNA structure prediction methods

Laboratory of Structural Bioinformatics @ Adam Mickiewicz University in Poznan

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Overview

Metric	CentroidAlifold(seed)		Afold
MCC	0.811	>	0.649
Average MCC ± 95% Confidence Intervals	0.803 ± 0.030	>	0.646 ± 0.046
Sensitivity	0.727	>	0.646
Positive Predictive Value	0.906	>	0.657
Total TP	2673	>	2373
Total TN	612705	>	612042
Total FP	527	<	1623
Total FP CONTRA	44	<	163
Total FP INCONS	234	<	1078
Total FP COMP	249	<	382
Total FN	1002	<	1302
P-value	3.56938820447e-08

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Performance plots

Comparison of performance of CentroidAlifold(seed) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(seed) and Afold).
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for CentroidAlifold(seed) and Afold).
Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(seed) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(seed) and Afold).

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Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP	2673
Total TN	612705
Total FP	527
Total FP CONTRA	44
Total FP INCONS	234
Total FP COMP	249
Total FN	1002

Total Scores
MCC	0.811
Average MCC ± 95% Confidence Intervals	0.803 ± 0.030
Sensitivity	0.727
Positive Predictive Value	0.906
Nr of predictions	162

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2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
PDB_00012	mir-TAR links to Rfam database...	1.00	1.00	1.00	7	399	2	0	0	2	0
PDB_00213	Gammaretro_CES links to Rfam database...	0.85	0.73	1.00	30	5020	0	0	0	0	11
PDB_00553	mir-TAR links to Rfam database...	0.95	0.91	1.00	10	455	0	0	0	0	1
PDB_00716	HDV_ribozyme links to Rfam database...	0.75	0.61	0.93	14	2686	1	0	1	0	9
PDB_00741	Entero_5_CRE links to Rfam database...	0.72	0.53	1.00	9	694	0	0	0	0	8
PDB_00810	s2m links to Rfam database...	0.87	0.76	1.00	13	1068	1	0	0	1	4
PDB_00828	Purine links to Rfam database...	0.88	0.78	1.00	21	2464	0	0	0	0	6
PDB_00829	Purine links to Rfam database...	0.91	0.83	1.00	20	2258	0	0	0	0	4
PDB_00876	HIV_FE links to Rfam database...	0.53	0.50	0.59	10	973	7	0	7	0	10
PDB_01050	UnaL2 links to Rfam database...	0.68	0.46	1.00	6	624	2	0	0	2	7
PDB_01051	Telomerase-cil links to Rfam database...	0.96	0.92	1.00	12	891	4	0	0	4	1
PDB_01092	glmS links to Rfam database...	0.72	0.58	0.91	30	10120	4	0	3	1	22
PDB_01152	HIV_FS2 links to Rfam database...	0.80	0.64	1.00	9	552	0	0	0	0	5
RFA_00389	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	3	0	0	3	1
RFA_00390	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	2	0	0	2	1
RFA_00391	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	3	0	0	3	1
RFA_00396	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	3	0	0	3	1
RFA_00402	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	3	0	0	3	1
RFA_00409	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	3	0	0	3	1
RFA_00416	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1471	2	0	0	2	1
RFA_00425	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1639	3	0	0	3	1
RFA_00427	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1471	3	0	0	3	1
RFA_00433	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	2	0	0	2	1
RFA_00434	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	3	0	0	3	1
RFA_00436	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	3	0	0	3	1
RFA_00440	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1471	3	0	0	3	1
RFA_00442	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	3	0	0	3	1
RFA_00444	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1526	3	0	0	3	1
RFA_00446	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1471	3	0	0	3	1
RFA_00449	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1471	3	0	0	3	1
RFA_00582	Y_RNA links to Rfam database...	1.00	1.00	1.00	15	5980	3	0	0	3	0
RFA_00583	Y_RNA links to Rfam database...	1.00	1.00	1.00	15	4935	3	0	0	3	0
RFA_00585	Y_RNA links to Rfam database...	1.00	1.00	1.00	15	4836	3	0	0	3	0
RFA_00587	Y_RNA links to Rfam database...	1.00	1.00	1.00	15	4836	3	0	0	3	0
RFA_00588	Y_RNA links to Rfam database...	1.00	1.00	1.00	15	4545	3	0	0	3	0
RFA_00589	Y_RNA links to Rfam database...	0.97	0.93	1.00	14	4357	3	0	0	3	1
RFA_00594	Y_RNA links to Rfam database...	1.00	1.00	1.00	15	2760	3	0	0	3	0
RFA_00596	Y_RNA links to Rfam database...	0.93	0.87	1.00	13	5982	3	0	0	3	2
RFA_00603	Telomerase-cil links to Rfam database...	0.96	0.91	1.00	32	13498	0	0	0	0	3
RFA_00604	Telomerase-cil links to Rfam database...	0.97	0.94	1.00	33	13497	0	0	0	0	2
RFA_00607	Telomerase-cil links to Rfam database...	0.94	0.89	1.00	32	17734	0	0	0	0	4
RFA_00609	Telomerase-cil links to Rfam database...	0.93	0.86	1.00	32	17923	0	0	0	0	5
RFA_00610	Telomerase-cil links to Rfam database...	0.93	0.86	1.00	32	17173	0	0	0	0	5
RFA_00611	Telomerase-cil links to Rfam database...	0.96	0.91	1.00	32	13009	0	0	0	0	3
RFA_00613	Telomerase-cil links to Rfam database...	0.97	0.94	1.00	33	12847	0	0	0	0	2
RFA_00615	Telomerase-cil links to Rfam database...	0.85	0.80	0.90	28	13335	3	0	3	0	7
RFA_00632	HDV_ribozyme links to Rfam database...	0.74	0.64	0.86	18	4074	3	2	1	0	10
RFA_00636	HDV_ribozyme links to Rfam database...	0.78	0.68	0.90	19	3984	2	2	0	0	9
RFA_00644	Vimentin3 links to Rfam database...	0.00	0.00	0.00	0	2701	0	0	0	0	18
RFA_00645	Vimentin3 links to Rfam database...	0.23	0.06	1.00	1	2414	0	0	0	0	17
RFA_00649	Vimentin3 links to Rfam database...	0.00	0.00	0.00	0	2145	0	0	0	0	18
RFA_00653	Vimentin3 links to Rfam database...	0.33	0.11	1.00	2	2143	0	0	0	0	16
RFA_00654	Vimentin3 links to Rfam database...	0.00	0.00	0.00	0	2415	0	0	0	0	18
RFA_00658	Hammerhead_1 links to Rfam database...	0.71	0.57	0.89	8	1119	2	0	1	1	6
RFA_00659	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	1122	0	0	0	0	8
RFA_00664	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	984	0	0	0	0	8
RFA_00667	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	984	0	0	0	0	8
RFA_00668	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	984	0	0	0	0	8
RFA_00672	Hammerhead_1 links to Rfam database...	0.78	0.62	1.00	8	895	0	0	0	0	5
RFA_00673	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	1122	0	0	0	0	8
RFA_00674	Hammerhead_1 links to Rfam database...	0.60	0.43	0.86	6	1121	1	0	1	0	8
RFA_00675	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	984	0	0	0	0	8
RFA_00677	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	984	0	0	0	0	8
RFA_00678	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	940	0	0	0	0	8
RFA_00680	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	1122	0	0	0	0	8
RFA_00684	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	984	0	0	0	0	8
RFA_00685	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	984	0	0	0	0	8
RFA_00695	Hammerhead_1 links to Rfam database...	0.80	0.64	1.00	9	7012	0	0	0	0	5
RFA_00703	Hammerhead_1 links to Rfam database...	0.80	0.64	1.00	9	4269	0	0	0	0	5
RFA_00704	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	984	0	0	0	0	8
RFA_00705	Hammerhead_1 links to Rfam database...	0.76	0.64	0.90	9	1025	2	0	1	1	5
RFA_00706	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	1029	0	0	0	0	8
RFA_00707	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	1029	0	0	0	0	8
RFA_00708	Hammerhead_1 links to Rfam database...	0.71	0.57	0.89	8	1026	2	0	1	1	6
RFA_00709	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	984	0	0	0	0	8
RFA_00710	Hammerhead_1 links to Rfam database...	0.72	0.64	0.82	9	979	3	0	2	1	5
RFA_00711	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	1029	0	0	0	0	8
RFA_00716	Hammerhead_1 links to Rfam database...	0.65	0.43	1.00	6	940	0	0	0	0	8
RFA_00717	Hammerhead_1 links to Rfam database...	0.75	0.57	1.00	8	895	0	0	0	0	6
RFA_00730	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00731	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00733	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00734	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00736	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00737	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00745	s2m links to Rfam database...	1.00	1.00	1.00	12	934	2	0	0	2	0
RFA_00749	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00758	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00762	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00763	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00764	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00765	s2m links to Rfam database...	1.00	1.00	1.00	12	891	2	0	0	2	0
RFA_00767	Corona_pk3 links to Rfam database...	0.74	0.56	1.00	10	1881	0	0	0	0	8
RFA_00768	Corona_pk3 links to Rfam database...	0.74	0.56	1.00	10	1881	0	0	0	0	8
RFA_00769	Corona_pk3 links to Rfam database...	0.74	0.56	1.00	10	1943	0	0	0	0	8
RFA_00770	Corona_pk3 links to Rfam database...	0.74	0.56	1.00	10	2006	0	0	0	0	8
RFA_00773	Corona_pk3 links to Rfam database...	0.74	0.56	1.00	10	1943	0	0	0	0	8
RFA_00781	Gammaretro_CES links to Rfam database...	0.97	0.94	1.00	30	5020	0	0	0	0	2
RFA_00786	Gammaretro_CES links to Rfam database...	0.97	0.94	1.00	30	5020	0	0	0	0	2
RFA_00791	Gammaretro_CES links to Rfam database...	0.97	0.94	1.00	30	5121	0	0	0	0	2
RFA_00792	Gammaretro_CES links to Rfam database...	0.97	0.94	1.00	30	5020	0	0	0	0	2
RFA_00801	Gammaretro_CES links to Rfam database...	0.97	0.94	1.00	30	5020	0	0	0	0	2
RFA_00808	RydC links to Rfam database...	0.65	0.56	0.75	9	2004	3	1	2	0	7
RFA_00809	RydC links to Rfam database...	0.43	0.38	0.50	6	2133	6	0	6	0	10
SRP_00001	Bacteria_large_SRP links to Rfam database...	0.82	0.68	1.00	27	6759	5	0	0	5	13
SRP_00008	Bacteria_small_SRP links to Rfam database...	0.96	0.92	1.00	23	2903	2	0	0	2	2
SRP_00038	Bacteria_small_SRP links to Rfam database...	0.90	0.82	1.00	27	5023	3	0	0	3	6
SRP_00040	Bacteria_small_SRP links to Rfam database...	0.55	0.52	0.59	16	5538	14	1	10	3	15
SRP_00042	Bacteria_small_SRP links to Rfam database...	0.85	0.80	0.91	20	3983	6	1	1	4	5
SRP_00043	Bacteria_small_SRP links to Rfam database...	0.42	0.41	0.43	12	5022	18	2	14	2	17
SRP_00044	Bacteria_small_SRP links to Rfam database...	0.85	0.81	0.90	26	6076	4	1	2	1	6
SRP_00051	Bacteria_small_SRP links to Rfam database...	0.76	0.67	0.87	20	5437	7	0	3	4	10
SRP_00054	Bacteria_small_SRP links to Rfam database...	0.92	0.84	1.00	27	5538	3	0	0	3	5
SRP_00072	Bacteria_small_SRP links to Rfam database...	0.68	0.66	0.70	19	6301	11	0	8	3	10
SRP_00074	Bacteria_small_SRP links to Rfam database...	0.52	0.48	0.56	14	6530	16	0	11	5	15
SRP_00075	Bacteria_small_SRP links to Rfam database...	0.34	0.32	0.37	11	5535	19	0	19	0	23
SRP_00077	Bacteria_small_SRP links to Rfam database...	0.59	0.51	0.68	19	6642	11	0	9	2	18
SRP_00081	Bacteria_small_SRP links to Rfam database...	0.65	0.65	0.67	20	5535	10	1	9	0	11
SRP_00084	Bacteria_small_SRP links to Rfam database...	0.88	0.82	0.93	28	5430	2	1	1	0	6
SRP_00094	Bacteria_small_SRP links to Rfam database...	0.82	0.83	0.80	20	4070	9	1	4	4	4
SRP_00095	Bacteria_small_SRP links to Rfam database...	0.82	0.84	0.81	21	3979	8	1	4	3	4
SRP_00098	Bacteria_small_SRP links to Rfam database...	0.65	0.57	0.75	21	6413	9	1	6	2	16
SRP_00105	Bacteria_small_SRP links to Rfam database...	0.89	0.79	1.00	27	5538	3	0	0	3	7
SRP_00106	Bacteria_large_SRP links to Rfam database...	0.69	0.72	0.67	18	5226	15	3	6	6	7
SRP_00107	Bacteria_small_SRP links to Rfam database...	0.46	0.53	0.40	10	3630	19	3	12	4	9
SRP_00128	Bacteria_small_SRP links to Rfam database...	0.82	0.72	0.93	26	6758	4	1	1	2	10
SRP_00141	Bacteria_small_SRP links to Rfam database...	0.78	0.66	0.93	27	6299	3	1	1	1	14
SRP_00145	Bacteria_small_SRP links to Rfam database...	0.81	0.70	0.93	28	6298	2	1	1	0	12
SRP_00146	Bacteria_small_SRP links to Rfam database...	0.83	0.75	0.93	27	5224	3	1	1	1	9
SRP_00161	Bacteria_small_SRP links to Rfam database...	0.84	0.82	0.86	18	2829	5	0	3	2	4
SRP_00162	Bacteria_small_SRP links to Rfam database...	0.87	0.87	0.87	20	2903	4	0	3	1	3
SRP_00164	Bacteria_small_SRP links to Rfam database...	0.78	0.66	0.92	23	6878	7	1	1	5	12
SRP_00200	Bacteria_small_SRP links to Rfam database...	0.77	0.67	0.89	24	6876	6	1	2	3	12
SRP_00209	Bacteria_small_SRP links to Rfam database...	0.75	0.74	0.77	20	4630	9	1	5	3	7
SRP_00216	Bacteria_small_SRP links to Rfam database...	0.93	0.93	0.93	25	3376	4	1	1	2	2
SRP_00222	Bacteria_small_SRP links to Rfam database...	0.87	0.84	0.91	21	3058	3	1	1	1	4
SRP_00227	Bacteria_small_SRP links to Rfam database...	0.86	0.81	0.93	25	5124	5	1	1	3	6
SRP_00231	Bacteria_small_SRP links to Rfam database...	0.88	0.82	0.93	28	5430	2	1	1	0	6
SRP_00233	Bacteria_small_SRP links to Rfam database...	0.87	0.82	0.93	27	5122	3	0	2	1	6
SRP_00243	Bacteria_small_SRP links to Rfam database...	0.88	0.81	0.96	25	5125	5	0	1	4	6
SRP_00250	Bacteria_small_SRP links to Rfam database...	0.67	0.58	0.78	21	6759	9	1	5	3	15
SRP_00251	Bacteria_small_SRP links to Rfam database...	0.77	0.67	0.89	24	6994	6	1	2	3	12
SRP_00271	Bacteria_small_SRP links to Rfam database...	0.89	0.88	0.91	21	3217	3	0	2	1	3
SRP_00273	Bacteria_small_SRP links to Rfam database...	0.79	0.68	0.93	27	6757	3	1	1	1	13
SRP_00274	Bacteria_small_SRP links to Rfam database...	0.81	0.71	0.93	27	6874	3	1	1	1	11
SRP_00295	Bacteria_small_SRP links to Rfam database...	0.78	0.66	0.93	25	6876	5	1	1	3	13
SRP_00303	Bacteria_small_SRP links to Rfam database...	0.68	0.63	0.74	20	6643	10	1	6	3	12
SRP_00310	Bacteria_small_SRP links to Rfam database...	0.82	0.83	0.83	19	2903	5	0	4	1	4
SRP_00312	Bacteria_small_SRP links to Rfam database...	0.91	0.89	0.92	24	4160	5	1	1	3	3
SRP_00315	Bacteria_small_SRP links to Rfam database...	0.81	0.83	0.79	19	2902	5	0	5	0	4
SRP_00318	Bacteria_small_SRP links to Rfam database...	0.81	0.83	0.79	19	2979	5	0	5	0	4
SRP_00324	Bacteria_small_SRP links to Rfam database...	0.62	0.59	0.65	17	5330	10	1	8	1	12
SRP_00325	Bacteria_small_SRP links to Rfam database...	0.87	0.82	0.93	27	4342	3	0	2	1	6
SRP_00338	Bacteria_small_SRP links to Rfam database...	0.90	0.81	1.00	29	5431	1	0	0	1	7
SRP_00342	Bacteria_small_SRP links to Rfam database...	0.72	0.72	0.72	18	3980	12	0	7	5	7
SRP_00350	Bacteria_small_SRP links to Rfam database...	0.84	0.78	0.91	21	3893	4	1	1	2	6
SRP_00356	Bacteria_small_SRP links to Rfam database...	0.80	0.73	0.88	22	5025	6	0	3	3	8
SRP_00357	Bacteria_small_SRP links to Rfam database...	0.82	0.72	0.93	26	5328	4	1	1	2	10
SRP_00365	Bacteria_small_SRP links to Rfam database...	0.84	0.78	0.91	21	3380	4	0	2	2	6
SRP_00367	Bacteria_small_SRP links to Rfam database...	0.79	0.69	0.92	24	6760	6	1	1	4	11
SRP_00369	Bacteria_small_SRP links to Rfam database...	0.78	0.66	0.92	23	5753	7	1	1	5	12
SRP_00383	Bacteria_small_SRP links to Rfam database...	0.92	0.92	0.92	22	3216	6	0	2	4	2

^top

Performance of Afold - scored lower in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP	2373
Total TN	612042
Total FP	1623
Total FP CONTRA	163
Total FP INCONS	1078
Total FP COMP	382
Total FN	1302

Total Scores
MCC	0.649
Average MCC ± 95% Confidence Intervals	0.646 ± 0.046
Sensitivity	0.646
Positive Predictive Value	0.657
Nr of predictions	162

^top

2. Individual counts for Afold [ download as .csv ]

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
PDB_00012	mir-TAR links to Rfam database...	1.00	1.00	1.00	7	399	3	0	0	3	0
PDB_00213	Gammaretro_CES links to Rfam database...	0.87	0.80	0.94	33	5015	2	0	2	0	8
PDB_00553	mir-TAR links to Rfam database...	1.00	1.00	1.00	11	454	0	0	0	0	0
PDB_00716	HDV_ribozyme links to Rfam database...	-0.01	0.00	0.00	0	2677	25	1	23	1	23
PDB_00741	Entero_5_CRE links to Rfam database...	0.87	0.76	1.00	13	690	0	0	0	0	4
PDB_00810	s2m links to Rfam database...	0.77	0.71	0.86	12	1067	2	0	2	0	5
PDB_00828	Purine links to Rfam database...	0.88	0.78	1.00	21	2464	0	0	0	0	6
PDB_00829	Purine links to Rfam database...	0.82	0.71	0.94	17	2260	1	0	1	0	7
PDB_00876	HIV_FE links to Rfam database...	0.97	0.95	1.00	19	971	0	0	0	0	1
PDB_01050	UnaL2 links to Rfam database...	0.96	0.92	1.00	12	618	2	0	0	2	1
PDB_01051	Telomerase-cil links to Rfam database...	0.75	0.69	0.82	9	892	6	0	2	4	4
PDB_01092	glmS links to Rfam database...	0.69	0.60	0.79	31	10114	11	1	7	3	21
PDB_01152	HIV_FS2 links to Rfam database...	0.96	0.93	1.00	13	548	0	0	0	0	1
RFA_00389	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1416	2	0	0	2	0
RFA_00390	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1416	2	0	0	2	0
RFA_00391	Hammerhead_3 links to Rfam database...	0.93	0.87	1.00	13	1418	2	0	0	2	2
RFA_00396	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	2	0	0	2	1
RFA_00402	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1416	1	0	0	1	0
RFA_00409	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1417	2	0	0	2	1
RFA_00416	Hammerhead_3 links to Rfam database...	0.93	0.93	0.93	14	1470	4	0	1	3	1
RFA_00425	Hammerhead_3 links to Rfam database...	0.93	0.87	1.00	13	1640	5	0	0	5	2
RFA_00427	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1471	3	0	0	3	1
RFA_00433	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1416	2	0	0	2	0
RFA_00434	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1416	2	0	0	2	0
RFA_00436	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1416	2	0	0	2	0
RFA_00440	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1470	2	0	0	2	0
RFA_00442	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1416	2	0	0	2	0
RFA_00444	Hammerhead_3 links to Rfam database...	1.00	1.00	1.00	15	1525	2	0	0	2	0
RFA_00446	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1471	3	0	0	3	1
RFA_00449	Hammerhead_3 links to Rfam database...	0.97	0.93	1.00	14	1471	3	0	0	3	1
RFA_00582	Y_RNA links to Rfam database...	0.87	0.87	0.87	13	5980	23	0	2	21	2
RFA_00583	Y_RNA links to Rfam database...	0.41	0.40	0.43	6	4936	22	0	8	14	9
RFA_00585	Y_RNA links to Rfam database...	0.87	0.87	0.87	13	4836	13	0	2	11	2
RFA_00587	Y_RNA links to Rfam database...	0.87	0.87	0.87	13	4836	14	0	2	12	2
RFA_00588	Y_RNA links to Rfam database...	0.79	0.73	0.85	11	4547	14	0	2	12	4
RFA_00589	Y_RNA links to Rfam database...	0.79	0.73	0.85	11	4358	18	0	2	16	4
RFA_00594	Y_RNA links to Rfam database...	0.83	0.80	0.86	12	2761	13	0	2	11	3
RFA_00596	Y_RNA links to Rfam database...	0.00	0.00	0.00	0	5980	24	4	11	9	15
RFA_00603	Telomerase-cil links to Rfam database...	0.64	0.69	0.60	24	13490	20	4	12	4	11
RFA_00604	Telomerase-cil links to Rfam database...	0.72	0.74	0.70	26	13493	24	2	9	13	9
RFA_00607	Telomerase-cil links to Rfam database...	0.57	0.61	0.54	22	17725	25	6	13	6	14
RFA_00609	Telomerase-cil links to Rfam database...	0.75	0.76	0.74	28	17917	28	2	8	18	9
RFA_00610	Telomerase-cil links to Rfam database...	0.77	0.76	0.78	28	17169	23	2	6	15	9
RFA_00611	Telomerase-cil links to Rfam database...	0.79	0.77	0.82	27	13008	13	0	6	7	8
RFA_00613	Telomerase-cil links to Rfam database...	0.61	0.60	0.62	21	12846	17	4	9	4	14
RFA_00615	Telomerase-cil links to Rfam database...	0.51	0.51	0.51	18	13331	18	8	9	1	17
RFA_00632	HDV_ribozyme links to Rfam database...	0.40	0.39	0.41	11	4068	18	0	16	2	17
RFA_00636	HDV_ribozyme links to Rfam database...	0.42	0.43	0.43	12	3977	17	2	14	1	16
RFA_00644	Vimentin3 links to Rfam database...	-0.01	0.00	0.00	0	2681	21	4	16	1	18
RFA_00645	Vimentin3 links to Rfam database...	-0.01	0.00	0.00	0	2401	15	3	11	1	18
RFA_00649	Vimentin3 links to Rfam database...	0.65	0.61	0.69	11	2129	8	1	4	3	7
RFA_00653	Vimentin3 links to Rfam database...	0.34	0.33	0.35	6	2128	12	3	8	1	12
RFA_00654	Vimentin3 links to Rfam database...	0.27	0.28	0.28	5	2397	14	2	11	1	13
RFA_00658	Hammerhead_1 links to Rfam database...	0.69	0.64	0.75	9	1116	5	0	3	2	5
RFA_00659	Hammerhead_1 links to Rfam database...	0.30	0.29	0.33	4	1116	10	1	7	2	10
RFA_00664	Hammerhead_1 links to Rfam database...	0.07	0.07	0.09	1	979	11	0	10	1	13
RFA_00667	Hammerhead_1 links to Rfam database...	0.30	0.29	0.33	4	978	8	1	7	0	10
RFA_00668	Hammerhead_1 links to Rfam database...	0.41	0.43	0.40	6	975	9	0	9	0	8
RFA_00672	Hammerhead_1 links to Rfam database...	0.17	0.15	0.20	2	893	9	0	8	1	11
RFA_00673	Hammerhead_1 links to Rfam database...	0.42	0.36	0.50	5	1118	6	0	5	1	9
RFA_00674	Hammerhead_1 links to Rfam database...	0.69	0.71	0.67	10	1113	6	0	5	1	4
RFA_00675	Hammerhead_1 links to Rfam database...	0.29	0.29	0.31	4	977	9	1	8	0	10
RFA_00677	Hammerhead_1 links to Rfam database...	0.42	0.43	0.43	6	976	9	0	8	1	8
RFA_00678	Hammerhead_1 links to Rfam database...	0.66	0.64	0.69	9	933	4	0	4	0	5
RFA_00680	Hammerhead_1 links to Rfam database...	0.74	0.71	0.77	10	1115	6	0	3	3	4
RFA_00684	Hammerhead_1 links to Rfam database...	0.66	0.64	0.69	9	977	5	0	4	1	5
RFA_00685	Hammerhead_1 links to Rfam database...	0.42	0.36	0.50	5	980	6	0	5	1	9
RFA_00695	Hammerhead_1 links to Rfam database...	0.67	0.64	0.69	9	7008	29	1	3	25	5
RFA_00703	Hammerhead_1 links to Rfam database...	0.67	0.64	0.69	9	4265	18	1	3	14	5
RFA_00704	Hammerhead_1 links to Rfam database...	0.48	0.43	0.55	6	979	7	0	5	2	8
RFA_00705	Hammerhead_1 links to Rfam database...	0.69	0.71	0.67	10	1020	5	0	5	0	4
RFA_00706	Hammerhead_1 links to Rfam database...	0.44	0.36	0.56	5	1026	4	0	4	0	9
RFA_00707	Hammerhead_1 links to Rfam database...	0.07	0.07	0.10	1	1025	9	3	6	0	13
RFA_00708	Hammerhead_1 links to Rfam database...	0.47	0.36	0.63	5	1027	3	0	3	0	9
RFA_00709	Hammerhead_1 links to Rfam database...	0.16	0.14	0.20	2	980	9	0	8	1	12
RFA_00710	Hammerhead_1 links to Rfam database...	0.23	0.21	0.27	3	979	8	0	8	0	11
RFA_00711	Hammerhead_1 links to Rfam database...	0.40	0.36	0.45	5	1024	6	0	6	0	9
RFA_00716	Hammerhead_1 links to Rfam database...	0.06	0.07	0.08	1	933	12	0	12	0	13
RFA_00717	Hammerhead_1 links to Rfam database...	0.64	0.64	0.64	9	889	5	0	5	0	5
RFA_00730	s2m links to Rfam database...	0.69	0.67	0.73	8	892	4	1	2	1	4
RFA_00731	s2m links to Rfam database...	0.66	0.67	0.67	8	891	5	1	3	1	4
RFA_00733	s2m links to Rfam database...	0.66	0.67	0.67	8	891	5	1	3	1	4
RFA_00734	s2m links to Rfam database...	0.61	0.67	0.57	8	889	8	1	5	2	4
RFA_00736	s2m links to Rfam database...	0.66	0.67	0.67	8	891	5	1	3	1	4
RFA_00737	s2m links to Rfam database...	1.00	1.00	1.00	12	891	1	0	0	1	0
RFA_00745	s2m links to Rfam database...	0.66	0.67	0.67	8	934	5	1	3	1	4
RFA_00749	s2m links to Rfam database...	0.66	0.67	0.67	8	891	5	1	3	1	4
RFA_00758	s2m links to Rfam database...	0.96	0.92	1.00	11	892	1	0	0	1	1
RFA_00762	s2m links to Rfam database...	0.64	0.67	0.62	8	890	6	1	4	1	4
RFA_00763	s2m links to Rfam database...	1.00	1.00	1.00	12	891	1	0	0	1	0
RFA_00764	s2m links to Rfam database...	0.66	0.67	0.67	8	891	5	1	3	1	4
RFA_00765	s2m links to Rfam database...	1.00	1.00	1.00	12	891	1	0	0	1	0
RFA_00767	Corona_pk3 links to Rfam database...	0.63	0.56	0.71	10	1877	5	0	4	1	8
RFA_00768	Corona_pk3 links to Rfam database...	0.48	0.44	0.53	8	1876	8	1	6	1	10
RFA_00769	Corona_pk3 links to Rfam database...	0.55	0.56	0.56	10	1935	10	3	5	2	8
RFA_00770	Corona_pk3 links to Rfam database...	0.68	0.56	0.83	10	2004	6	0	2	4	8
RFA_00773	Corona_pk3 links to Rfam database...	0.71	0.56	0.91	10	1942	5	1	0	4	8
RFA_00781	Gammaretro_CES links to Rfam database...	0.55	0.56	0.55	18	5017	17	2	13	2	14
RFA_00786	Gammaretro_CES links to Rfam database...	0.71	0.72	0.70	23	5017	12	2	8	2	9
RFA_00791	Gammaretro_CES links to Rfam database...	0.50	0.50	0.52	16	5120	16	3	12	1	16
RFA_00792	Gammaretro_CES links to Rfam database...	0.90	0.88	0.93	28	5020	3	0	2	1	4
RFA_00801	Gammaretro_CES links to Rfam database...	0.59	0.59	0.59	19	5018	14	0	13	1	13
RFA_00808	RydC links to Rfam database...	-0.01	0.00	0.00	0	2001	16	2	13	1	16
RFA_00809	RydC links to Rfam database...	0.36	0.38	0.35	6	2128	12	1	10	1	10
SRP_00001	Bacteria_large_SRP links to Rfam database...	0.89	0.90	0.88	36	6745	5	1	4	0	4
SRP_00008	Bacteria_small_SRP links to Rfam database...	0.70	0.72	0.69	18	2900	9	0	8	1	7
SRP_00038	Bacteria_small_SRP links to Rfam database...	-0.01	0.00	0.00	0	5019	31	2	29	0	33
SRP_00040	Bacteria_small_SRP links to Rfam database...	0.70	0.74	0.66	23	5530	14	1	11	2	8
SRP_00042	Bacteria_small_SRP links to Rfam database...	0.38	0.40	0.37	10	3978	19	1	16	2	15
SRP_00043	Bacteria_small_SRP links to Rfam database...	0.45	0.48	0.42	14	5017	23	4	15	4	15
SRP_00044	Bacteria_small_SRP links to Rfam database...	0.77	0.75	0.80	24	6075	10	1	5	4	8
SRP_00051	Bacteria_small_SRP links to Rfam database...	0.09	0.10	0.09	3	5428	29	1	28	0	27
SRP_00054	Bacteria_small_SRP links to Rfam database...	-0.01	0.00	0.00	0	5531	34	3	31	0	32
SRP_00072	Bacteria_small_SRP links to Rfam database...	0.00	0.00	0.00	0	6296	32	3	29	0	29
SRP_00074	Bacteria_small_SRP links to Rfam database...	0.39	0.41	0.38	12	6523	24	3	17	4	17
SRP_00075	Bacteria_small_SRP links to Rfam database...	0.82	0.79	0.84	27	5533	8	0	5	3	7
SRP_00077	Bacteria_small_SRP links to Rfam database...	0.15	0.16	0.15	6	6630	34	4	30	0	31
SRP_00081	Bacteria_small_SRP links to Rfam database...	0.68	0.74	0.62	23	5528	14	1	13	0	8
SRP_00084	Bacteria_small_SRP links to Rfam database...	0.81	0.82	0.80	28	5425	7	1	6	0	6
SRP_00094	Bacteria_small_SRP links to Rfam database...	0.86	0.88	0.84	21	4070	4	0	4	0	3
SRP_00095	Bacteria_small_SRP links to Rfam database...	0.81	0.84	0.78	21	3978	6	1	5	0	4
SRP_00098	Bacteria_small_SRP links to Rfam database...	0.66	0.68	0.66	25	6403	14	1	12	1	12
SRP_00105	Bacteria_small_SRP links to Rfam database...	-0.01	0.00	0.00	0	5532	33	4	29	0	34
SRP_00106	Bacteria_large_SRP links to Rfam database...	0.67	0.76	0.59	19	5221	16	4	9	3	6
SRP_00107	Bacteria_small_SRP links to Rfam database...	0.13	0.16	0.12	3	3629	26	6	17	3	16
SRP_00128	Bacteria_small_SRP links to Rfam database...	0.77	0.81	0.74	29	6747	12	1	9	2	7
SRP_00141	Bacteria_small_SRP links to Rfam database...	0.86	0.85	0.88	35	6288	5	1	4	0	6
SRP_00145	Bacteria_small_SRP links to Rfam database...	0.96	0.98	0.95	39	6287	3	1	1	1	1
SRP_00146	Bacteria_small_SRP links to Rfam database...	0.93	0.94	0.92	34	5216	3	1	2	0	2
SRP_00161	Bacteria_small_SRP links to Rfam database...	0.80	0.82	0.78	18	2827	5	0	5	0	4
SRP_00162	Bacteria_small_SRP links to Rfam database...	0.81	0.83	0.79	19	2902	6	0	5	1	4
SRP_00164	Bacteria_small_SRP links to Rfam database...	0.87	0.89	0.86	31	6867	6	1	4	1	4
SRP_00200	Bacteria_small_SRP links to Rfam database...	0.44	0.44	0.43	16	6866	21	2	19	0	20
SRP_00209	Bacteria_small_SRP links to Rfam database...	0.73	0.74	0.71	20	4628	8	0	8	0	7
SRP_00216	Bacteria_small_SRP links to Rfam database...	0.93	0.93	0.93	25	3376	3	1	1	1	2
SRP_00222	Bacteria_small_SRP links to Rfam database...	0.94	0.96	0.92	24	3055	3	1	1	1	1
SRP_00227	Bacteria_small_SRP links to Rfam database...	0.89	0.90	0.88	28	5119	4	1	3	0	3
SRP_00231	Bacteria_small_SRP links to Rfam database...	0.46	0.47	0.46	16	5425	19	1	18	0	18
SRP_00233	Bacteria_small_SRP links to Rfam database...	0.91	0.88	0.94	29	5120	2	0	2	0	4
SRP_00243	Bacteria_small_SRP links to Rfam database...	0.90	0.87	0.93	27	5122	3	0	2	1	4
SRP_00250	Bacteria_small_SRP links to Rfam database...	0.74	0.75	0.73	27	6749	13	1	9	3	9
SRP_00251	Bacteria_small_SRP links to Rfam database...	0.70	0.72	0.68	26	6983	12	1	11	0	10
SRP_00271	Bacteria_small_SRP links to Rfam database...	-0.01	0.00	0.00	0	3215	25	3	22	0	24
SRP_00273	Bacteria_small_SRP links to Rfam database...	0.86	0.88	0.85	35	6745	8	1	5	2	5
SRP_00274	Bacteria_small_SRP links to Rfam database...	0.91	0.92	0.90	35	6864	5	1	3	1	3
SRP_00295	Bacteria_small_SRP links to Rfam database...	0.88	0.87	0.89	33	6866	6	1	3	2	5
SRP_00303	Bacteria_small_SRP links to Rfam database...	0.60	0.63	0.59	20	6636	14	1	13	0	12
SRP_00310	Bacteria_small_SRP links to Rfam database...	0.81	0.83	0.79	19	2902	6	0	5	1	4
SRP_00312	Bacteria_small_SRP links to Rfam database...	0.29	0.30	0.29	8	4158	20	4	16	0	19
SRP_00315	Bacteria_small_SRP links to Rfam database...	0.78	0.78	0.78	18	2903	5	0	5	0	5
SRP_00318	Bacteria_small_SRP links to Rfam database...	0.78	0.78	0.78	18	2980	5	0	5	0	5
SRP_00324	Bacteria_small_SRP links to Rfam database...	0.58	0.62	0.55	18	5323	15	4	11	0	11
SRP_00325	Bacteria_small_SRP links to Rfam database...	1.00	1.00	1.00	33	4338	0	0	0	0	0
SRP_00338	Bacteria_small_SRP links to Rfam database...	0.92	0.92	0.92	33	5424	4	0	3	1	3
SRP_00342	Bacteria_small_SRP links to Rfam database...	0.57	0.60	0.56	15	3978	17	1	11	5	10
SRP_00350	Bacteria_small_SRP links to Rfam database...	0.26	0.26	0.27	7	3890	19	2	17	0	20
SRP_00356	Bacteria_small_SRP links to Rfam database...	0.65	0.67	0.65	20	5019	14	2	9	3	10
SRP_00357	Bacteria_small_SRP links to Rfam database...	0.93	0.92	0.94	33	5321	3	1	1	1	3
SRP_00365	Bacteria_small_SRP links to Rfam database...	0.75	0.74	0.77	20	3377	6	0	6	0	7
SRP_00367	Bacteria_small_SRP links to Rfam database...	0.83	0.86	0.81	30	6749	7	2	5	0	5
SRP_00369	Bacteria_small_SRP links to Rfam database...	0.93	0.91	0.94	32	5744	2	1	1	0	3
SRP_00383	Bacteria_small_SRP links to Rfam database...	0.12	0.13	0.13	3	3216	21	3	18	0	21

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.

Table of contents:

Overview

Performance plots

Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

Performance of Afold - scored lower in this pairwise comparison

1. Total counts & total scores for Afold

2. Individual counts for Afold [ download as .csv ]