CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold Murlet(seed)
MCC 0.718 > 0.468
Average MCC ± 95% Confidence Intervals 0.693 ± 0.066 > 0.340 ± 0.080
Sensitivity 0.666 > 0.266
Positive Predictive Value 0.777 < 0.828
Total TP 1190 > 475
Total TN 306775 < 307733
Total FP 438 > 103
Total FP CONTRA 57 > 0
Total FP INCONS 285 > 99
Total FP COMP 96 > 4
Total FN 596 < 1311
P-value 3.56938820447e-08

^top




Performance plots


  1. Comparison of performance of ContextFold and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and Murlet(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for ContextFold and Murlet(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and Murlet(seed)).

^top





Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 1190
Total TN 306775
Total FP 438
Total FP CONTRA 57
Total FP INCONS 285
Total FP COMP 96
Total FN 596
Total Scores
MCC 0.718
Average MCC ± 95% Confidence Intervals 0.693 ± 0.066
Sensitivity 0.666
Positive Predictive Value 0.777
Nr of predictions 91

^top



2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
PDB_00005 0.42 0.36 0.50 5 936 5 0 5 0 9
PDB_00012 1.00 1.00 1.00 7 399 2 0 0 2 0
PDB_00213 0.90 0.85 0.95 35 5013 2 0 2 0 6
PDB_00553 0.95 0.91 1.00 10 455 0 0 0 0 1
PDB_00716 -0.01 0.00 0.00 0 2687 14 0 14 0 23
PDB_00810 0.91 0.82 1.00 14 1067 0 0 0 0 3
PDB_01050 0.96 0.92 1.00 12 618 1 0 0 1 1
PDB_01051 0.96 0.92 1.00 12 891 4 0 0 4 1
PDB_01092 0.70 0.63 0.77 33 10110 12 1 9 2 19
PDB_01152 0.88 0.79 1.00 11 550 0 0 0 0 3
RFA_00390 1.00 1.00 1.00 15 1416 0 0 0 0 0
RFA_00416 1.00 1.00 1.00 15 1470 1 0 0 1 0
RFA_00433 1.00 1.00 1.00 15 1416 0 0 0 0 0
RFA_00587 1.00 1.00 1.00 15 4836 11 0 0 11 0
RFA_00603 0.63 0.60 0.66 21 13498 12 5 6 1 14
RFA_00604 0.73 0.69 0.77 24 13499 17 2 5 10 11
RFA_00605 0.20 0.17 0.24 6 15200 26 5 14 7 29
RFA_00607 0.85 0.75 0.96 27 17738 10 0 1 9 9
RFA_00609 0.68 0.65 0.71 24 17921 17 2 8 7 13
RFA_00610 0.90 0.86 0.94 32 17171 7 0 2 5 5
RFA_00611 0.93 0.86 1.00 30 13011 0 0 0 0 5
RFA_00613 0.68 0.66 0.70 23 12847 11 4 6 1 12
RFA_00615 0.67 0.60 0.75 21 13338 7 6 1 0 14
RFA_00632 0.25 0.25 0.26 7 4068 20 1 19 0 21
RFA_00636 0.52 0.43 0.63 12 3986 7 0 7 0 16
RFA_00642 0.44 0.39 0.50 7 2912 7 2 5 0 11
RFA_00643 0.47 0.39 0.58 7 2199 5 0 5 0 11
RFA_00644 0.77 0.83 0.71 15 2680 6 3 3 0 3
RFA_00645 -0.01 0.00 0.00 0 2402 13 2 11 0 18
RFA_00649 0.88 0.83 0.94 15 2129 1 0 1 0 3
RFA_00651 0.59 0.50 0.69 9 2067 4 0 4 0 9
RFA_00653 0.25 0.22 0.29 4 2131 10 2 8 0 14
RFA_00654 0.71 0.67 0.75 12 2399 5 1 3 1 6
RFA_00658 0.89 0.79 1.00 11 1117 0 0 0 0 3
RFA_00659 0.53 0.43 0.67 6 1119 3 0 3 0 8
RFA_00664 -0.01 0.00 0.00 0 980 11 0 10 1 14
RFA_00667 0.33 0.29 0.40 4 980 7 0 6 1 10
RFA_00668 0.67 0.57 0.80 8 980 2 0 2 0 6
RFA_00672 -0.01 0.00 0.00 0 895 8 0 8 0 13
RFA_00673 0.80 0.64 1.00 9 1119 0 0 0 0 5
RFA_00674 0.92 0.86 1.00 12 1116 1 0 0 1 2
RFA_00675 0.80 0.64 1.00 9 981 0 0 0 0 5
RFA_00677 0.67 0.57 0.80 8 980 2 0 2 0 6
RFA_00678 0.84 0.71 1.00 10 936 0 0 0 0 4
RFA_00680 0.92 0.86 1.00 12 1116 1 0 0 1 2
RFA_00684 0.77 0.71 0.83 10 978 2 0 2 0 4
RFA_00685 0.71 0.57 0.89 8 981 1 0 1 0 6
RFA_00695 0.00 0.00 0.00 0 7006 23 2 13 8 14
RFA_00703 0.46 0.43 0.50 6 4266 14 0 6 8 8
RFA_00704 0.50 0.43 0.60 6 980 5 0 4 1 8
RFA_00705 0.84 0.71 1.00 10 1025 0 0 0 0 4
RFA_00706 0.84 0.71 1.00 10 1025 0 0 0 0 4
RFA_00707 0.89 0.79 1.00 11 1024 0 0 0 0 3
RFA_00708 -0.01 0.00 0.00 0 1029 6 0 6 0 14
RFA_00709 0.16 0.14 0.20 2 980 9 0 8 1 12
RFA_00710 0.40 0.36 0.45 5 979 6 0 6 0 9
RFA_00711 -0.01 0.00 0.00 0 1024 12 0 11 1 14
RFA_00715 -0.01 0.00 0.00 0 936 10 0 10 0 14
RFA_00716 -0.01 0.00 0.00 0 938 8 0 8 0 14
RFA_00717 0.88 0.79 1.00 11 892 0 0 0 0 3
RFA_00730 1.00 1.00 1.00 12 891 1 0 0 1 0
RFA_00731 1.00 1.00 1.00 12 891 1 0 0 1 0
RFA_00733 1.00 1.00 1.00 12 891 1 0 0 1 0
RFA_00734 0.78 0.75 0.82 9 892 3 0 2 1 3
RFA_00736 1.00 1.00 1.00 12 891 1 0 0 1 0
RFA_00737 1.00 1.00 1.00 12 891 1 0 0 1 0
RFA_00745 1.00 1.00 1.00 12 934 1 0 0 1 0
RFA_00749 1.00 1.00 1.00 12 891 1 0 0 1 0
RFA_00758 0.96 0.92 1.00 11 892 0 0 0 0 1
RFA_00762 0.96 0.92 1.00 11 892 0 0 0 0 1
RFA_00763 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00764 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00765 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00767 0.59 0.56 0.63 10 1875 6 3 3 0 8
RFA_00768 0.61 0.56 0.67 10 1876 5 2 3 0 8
RFA_00769 0.55 0.56 0.56 10 1935 8 4 4 0 8
RFA_00770 0.61 0.56 0.67 10 2001 5 2 3 0 8
RFA_00773 0.59 0.56 0.63 10 1937 6 1 5 0 8
RFA_00779 0.61 0.56 0.67 10 1938 5 2 3 0 8
RFA_00781 1.00 1.00 1.00 32 5018 0 0 0 0 0
RFA_00786 0.97 0.94 1.00 30 5020 0 0 0 0 2
RFA_00791 0.94 0.88 1.00 28 5123 1 0 0 1 4
RFA_00792 0.76 0.75 0.77 24 5019 7 2 5 0 8
RFA_00801 0.97 0.94 1.00 30 5020 1 0 0 1 2
RFA_00808 0.58 0.44 0.78 7 2007 2 0 2 0 9
RFA_00809 0.39 0.31 0.50 5 2135 6 0 5 1 11
SRP_00137 0.77 0.80 0.74 20 4159 7 3 4 0 5
SRP_00141 0.99 0.98 1.00 40 6288 0 0 0 0 1
SRP_00146 1.00 1.00 1.00 36 5217 0 0 0 0 0
SRP_00285 1.00 1.00 1.00 30 3711 0 0 0 0 0
SRP_00338 0.96 0.94 0.97 34 5425 1 0 1 0 2

^top



Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 475
Total TN 307733
Total FP 103
Total FP CONTRA 0
Total FP INCONS 99
Total FP COMP 4
Total FN 1311
Total Scores
MCC 0.468
Average MCC ± 95% Confidence Intervals 0.340 ± 0.080
Sensitivity 0.266
Positive Predictive Value 0.828
Nr of predictions 91

^top



2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
PDB_00005 0.53 0.29 1.00 4 942 2 0 0 2 10
PDB_00012 0.65 0.43 1.00 3 403 0 0 0 0 4
PDB_00213 0.73 0.59 0.92 24 5024 2 0 2 0 17
PDB_00553 0.45 0.27 0.75 3 461 1 0 1 0 8
PDB_00716 0.23 0.13 0.43 3 2694 4 0 4 0 20
PDB_00810 0.63 0.53 0.75 9 1069 3 0 3 0 8
PDB_01050 0.55 0.31 1.00 4 626 1 0 0 1 9
PDB_01051 0.00 0.00 0.00 0 903 0 0 0 0 13
PDB_01092 0.69 0.48 1.00 25 10128 0 0 0 0 27
PDB_01152 0.76 0.64 0.90 9 551 1 0 1 0 5
RFA_00390 0.00 0.00 0.00 0 1431 0 0 0 0 15
RFA_00416 0.00 0.00 0.00 0 1485 0 0 0 0 15
RFA_00433 0.00 0.00 0.00 0 1431 0 0 0 0 15
RFA_00587 0.00 0.00 0.00 0 4851 0 0 0 0 15
RFA_00603 0.00 0.00 0.00 0 13530 0 0 0 0 35
RFA_00604 0.00 0.00 0.00 0 13530 0 0 0 0 35
RFA_00605 0.00 0.00 0.00 0 15225 0 0 0 0 35
RFA_00607 0.00 0.00 0.00 0 17766 0 0 0 0 36
RFA_00609 0.00 0.00 0.00 0 17955 0 0 0 0 37
RFA_00610 0.00 0.00 0.00 0 17205 0 0 0 0 37
RFA_00611 0.00 0.00 0.00 0 13041 0 0 0 0 35
RFA_00613 0.00 0.00 0.00 0 12880 0 0 0 0 35
RFA_00615 0.00 0.00 0.00 0 13366 0 0 0 0 35
RFA_00632 0.21 0.11 0.43 3 4088 4 0 4 0 25
RFA_00636 0.21 0.11 0.43 3 3998 4 0 4 0 25
RFA_00642 0.57 0.44 0.73 8 2915 3 0 3 0 10
RFA_00643 -0.01 0.00 0.00 0 2203 8 0 8 0 18
RFA_00644 0.42 0.33 0.55 6 2690 5 0 5 0 12
RFA_00645 0.00 0.00 0.00 0 2407 8 0 8 0 18
RFA_00649 -0.01 0.00 0.00 0 2137 8 0 8 0 18
RFA_00651 0.42 0.33 0.55 6 2069 5 0 5 0 12
RFA_00653 -0.01 0.00 0.00 0 2137 8 0 8 0 18
RFA_00654 0.57 0.44 0.73 8 2404 3 0 3 0 10
RFA_00658 0.00 0.00 0.00 0 1128 0 0 0 0 14
RFA_00659 0.00 0.00 0.00 0 1128 0 0 0 0 14
RFA_00664 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00667 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00668 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00672 0.00 0.00 0.00 0 903 0 0 0 0 13
RFA_00673 0.00 0.00 0.00 0 1128 0 0 0 0 14
RFA_00674 0.00 0.00 0.00 0 1128 0 0 0 0 14
RFA_00675 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00677 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00678 0.00 0.00 0.00 0 946 0 0 0 0 14
RFA_00680 0.00 0.00 0.00 0 1128 0 0 0 0 14
RFA_00684 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00685 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00695 0.00 0.00 0.00 0 7021 0 0 0 0 14
RFA_00703 0.00 0.00 0.00 0 4278 0 0 0 0 14
RFA_00704 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00705 0.00 0.00 0.00 0 1035 0 0 0 0 14
RFA_00706 0.00 0.00 0.00 0 1035 0 0 0 0 14
RFA_00707 0.00 0.00 0.00 0 1035 0 0 0 0 14
RFA_00708 0.00 0.00 0.00 0 1035 0 0 0 0 14
RFA_00709 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00710 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00711 0.00 0.00 0.00 0 1035 0 0 0 0 14
RFA_00715 0.00 0.00 0.00 0 946 0 0 0 0 14
RFA_00716 0.00 0.00 0.00 0 946 0 0 0 0 14
RFA_00717 0.00 0.00 0.00 0 903 0 0 0 0 14
RFA_00730 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00731 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00733 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00734 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00736 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00737 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00745 1.00 1.00 1.00 12 934 0 0 0 0 0
RFA_00749 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00758 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00762 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00763 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00764 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00765 1.00 1.00 1.00 12 891 0 0 0 0 0
RFA_00767 0.47 0.33 0.67 6 1882 3 0 3 0 12
RFA_00768 0.41 0.28 0.63 5 1883 3 0 3 0 13
RFA_00769 0.57 0.44 0.73 8 1942 3 0 3 0 10
RFA_00770 0.57 0.44 0.73 8 2005 3 0 3 0 10
RFA_00773 0.41 0.28 0.63 5 1945 3 0 3 0 13
RFA_00779 0.47 0.33 0.67 6 1944 3 0 3 0 12
RFA_00781 0.83 0.75 0.92 24 5024 2 0 2 0 8
RFA_00786 0.83 0.75 0.92 24 5024 2 0 2 0 8
RFA_00791 0.83 0.75 0.92 24 5125 2 0 2 0 8
RFA_00792 0.83 0.75 0.92 24 5024 2 0 2 0 8
RFA_00801 0.80 0.72 0.88 23 5024 3 0 3 0 9
RFA_00808 0.75 0.56 1.00 9 2007 0 0 0 0 7
RFA_00809 0.50 0.38 0.67 6 2136 3 0 3 0 10
SRP_00137 0.49 0.24 1.00 6 4180 0 0 0 0 19
SRP_00141 0.35 0.12 1.00 5 6323 1 0 0 1 36
SRP_00146 0.41 0.17 1.00 6 5247 0 0 0 0 30
SRP_00285 0.45 0.20 1.00 6 3735 0 0 0 0 24
SRP_00338 0.41 0.17 1.00 6 5454 0 0 0 0 30

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.