CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of NanoFolder - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for NanoFolder & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric NanoFolder Multilign(seed)
MCC 0.560 > 0.551
Average MCC ± 95% Confidence Intervals 0.535 ± 0.621 > 0.486 ± 0.341
Sensitivity 0.605 > 0.457
Positive Predictive Value 0.527 < 0.673
Total TP 49 > 37
Total TN 8367 < 8405
Total FP 59 > 19
Total FP CONTRA 12 > 2
Total FP INCONS 32 > 16
Total FP COMP 15 > 1
Total FN 32 < 44
P-value 0.0

^top




Performance plots


  1. Comparison of performance of NanoFolder and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for NanoFolder and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for NanoFolder and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for NanoFolder and Multilign(seed)).

^top





Performance of NanoFolder - scored higher in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 49
Total TN 8367
Total FP 59
Total FP CONTRA 12
Total FP INCONS 32
Total FP COMP 15
Total FN 32
Total Scores
MCC 0.560
Average MCC ± 95% Confidence Intervals 0.535 ± 0.621
Sensitivity 0.605
Positive Predictive Value 0.527
Nr of predictions 5

^top



2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00416 0.94 1.00 0.88 15 1468 6 2 0 4 0
RFA_00664 -0.01 0.00 0.00 0 978 13 0 12 1 14
RFA_00770 -0.01 0.00 0.00 0 1996 24 0 20 4 18
RFA_00773 0.93 1.00 0.86 18 1932 9 3 0 6 0
RFA_00808 0.83 1.00 0.70 16 1993 7 7 0 0 0

^top



Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 37
Total TN 8405
Total FP 19
Total FP CONTRA 2
Total FP INCONS 16
Total FP COMP 1
Total FN 44
Total Scores
MCC 0.551
Average MCC ± 95% Confidence Intervals 0.486 ± 0.341
Sensitivity 0.457
Positive Predictive Value 0.673
Nr of predictions 5

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00416 0.57 0.53 0.62 8 1472 6 1 4 1 7
RFA_00664 0.00 0.00 0.00 0 990 0 0 0 0 14
RFA_00770 0.68 0.56 0.83 10 2004 2 0 2 0 8
RFA_00773 0.59 0.56 0.63 10 1937 6 1 5 0 8
RFA_00808 0.60 0.56 0.64 9 2002 5 0 5 0 7

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.