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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Multilign(seed)
MCC 0.473 > 0.334
Average MCC ± 95% Confidence Intervals 0.318 ± 1.394 > 0.190 ± 0.816
Sensitivity 0.326 > 0.186
Positive Predictive Value 0.700 > 0.615
Total TP 14 > 8
Total TN 3583 < 3590
Total FP 9 > 6
Total FP CONTRA 0 < 1
Total FP INCONS 6 > 4
Total FP COMP 3 > 1
Total FN 29 < 35
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Multilign(seed)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 14
Total TN 3583
Total FP 9
Total FP CONTRA 0
Total FP INCONS 6
Total FP COMP 3
Total FN 29
Total Scores
MCC 0.473
Average MCC ± 95% Confidence Intervals 0.318 ± 1.394
Sensitivity 0.326
Positive Predictive Value 0.700
Nr of predictions 3

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00416 0.97 0.93 1.00 14 1471 2 0 0 2 1
RFA_00658 0.00 0.00 0.00 0 1126 3 0 2 1 14
RFA_00664 -0.01 0.00 0.00 0 986 4 0 4 0 14

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 8
Total TN 3590
Total FP 6
Total FP CONTRA 1
Total FP INCONS 4
Total FP COMP 1
Total FN 35
Total Scores
MCC 0.334
Average MCC ± 95% Confidence Intervals 0.190 ± 0.816
Sensitivity 0.186
Positive Predictive Value 0.615
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00416 0.57 0.53 0.62 8 1472 6 1 4 1 7
RFA_00658 0.00 0.00 0.00 0 1128 0 0 0 0 14
RFA_00664 0.00 0.00 0.00 0 990 0 0 0 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.