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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric RNASampler(20) Multilign(seed)
MCC 0.536 > 0.334
Average MCC ± 95% Confidence Intervals 0.331 ± 1.438 > 0.190 ± 0.816
Sensitivity 0.349 > 0.186
Positive Predictive Value 0.833 > 0.615
Total TP 15 > 8
Total TN 3585 < 3590
Total FP 7 > 6
Total FP CONTRA 0 < 1
Total FP INCONS 3 < 4
Total FP COMP 4 > 1
Total FN 28 < 35
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(20) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and Multilign(seed)).

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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 15
Total TN 3585
Total FP 7
Total FP CONTRA 0
Total FP INCONS 3
Total FP COMP 4
Total FN 28
Total Scores
MCC 0.536
Average MCC ± 95% Confidence Intervals 0.331 ± 1.438
Sensitivity 0.349
Positive Predictive Value 0.833
Nr of predictions 3

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00416 1.00 1.00 1.00 15 1470 2 0 0 2 0
RFA_00658 -0.01 0.00 0.00 0 1125 5 0 3 2 14
RFA_00664 0.00 0.00 0.00 0 990 0 0 0 0 14

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Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 8
Total TN 3590
Total FP 6
Total FP CONTRA 1
Total FP INCONS 4
Total FP COMP 1
Total FN 35
Total Scores
MCC 0.334
Average MCC ± 95% Confidence Intervals 0.190 ± 0.816
Sensitivity 0.186
Positive Predictive Value 0.615
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00416 0.57 0.53 0.62 8 1472 6 1 4 1 7
RFA_00658 0.00 0.00 0.00 0 1128 0 0 0 0 14
RFA_00664 0.00 0.00 0.00 0 990 0 0 0 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.