CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Carnac(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Carnac(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric Carnac(20) Carnac(seed)
MCC 0.444 > 0.000
Average MCC ± 95% Confidence Intervals 0.378 ± 0.153 > 0.000 ± 0.000
Sensitivity 0.219 > 0.000
Positive Predictive Value 0.903 > 0.000
Total TP 290 > 0
Total TN 737754 < 738075
Total FP 44 > 0
Total FP CONTRA 1 > 0
Total FP INCONS 30 > 0
Total FP COMP 13 > 0
Total FN 1034 < 1324
P-value 2.48055519165e-08

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Performance plots


  1. Comparison of performance of Carnac(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Carnac(20) and Carnac(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Carnac(20) and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Carnac(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Carnac(20) and Carnac(seed)).

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Performance of Carnac(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Carnac(20)

Total Base Pair Counts
Total TP 290
Total TN 737754
Total FP 44
Total FP CONTRA 1
Total FP INCONS 30
Total FP COMP 13
Total FN 1034
Total Scores
MCC 0.444
Average MCC ± 95% Confidence Intervals 0.378 ± 0.153
Sensitivity 0.219
Positive Predictive Value 0.903
Nr of predictions 13

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2. Individual counts for Carnac(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.00 0.00 0.00 0 101475 0 0 0 0 111
RFA_00601 0.00 0.00 0.00 0 99235 0 0 0 0 114
RFA_00602 0.00 0.00 0.00 0 101475 0 0 0 0 116
SRP_00011 0.57 0.33 1.00 34 46326 1 0 0 1 70
SRP_00015 0.65 0.46 0.90 46 46309 7 0 5 2 53
SRP_00152 0.58 0.39 0.87 40 45707 6 0 6 0 63
SRP_00178 0.53 0.28 1.00 29 45724 2 0 0 2 73
SRP_00179 0.70 0.50 0.96 53 46001 5 0 2 3 52
SRP_00181 0.56 0.31 1.00 32 46024 2 0 0 2 70
SRP_00182 0.43 0.22 0.85 22 46030 4 0 4 0 79
SRP_00184 0.35 0.16 0.76 16 46035 8 0 5 3 84
SRP_00188 0.24 0.11 0.53 9 31108 8 1 7 0 70
SRP_00308 0.30 0.10 0.90 9 36305 1 0 1 0 79

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 0
Total TN 738075
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 1324
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 13

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.00 0.00 0.00 0 101475 0 0 0 0 111
RFA_00601 0.00 0.00 0.00 0 99235 0 0 0 0 114
RFA_00602 0.00 0.00 0.00 0 101475 0 0 0 0 116
SRP_00011 0.00 0.00 0.00 0 46360 0 0 0 0 104
SRP_00015 0.00 0.00 0.00 0 46360 0 0 0 0 99
SRP_00152 0.00 0.00 0.00 0 45753 0 0 0 0 103
SRP_00178 0.00 0.00 0.00 0 45753 0 0 0 0 102
SRP_00179 0.00 0.00 0.00 0 46056 0 0 0 0 105
SRP_00181 0.00 0.00 0.00 0 46056 0 0 0 0 102
SRP_00182 0.00 0.00 0.00 0 46056 0 0 0 0 101
SRP_00184 0.00 0.00 0.00 0 46056 0 0 0 0 100
SRP_00188 0.00 0.00 0.00 0 31125 0 0 0 0 79
SRP_00308 0.00 0.00 0.00 0 36315 0 0 0 0 88

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.