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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

  4. Performance of PPfold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(20) & PPfold(seed) [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(20) PPfold(seed)
MCC 0.908 > 0.847
Average MCC ± 95% Confidence Intervals 0.908 ± > 0.847 ±
Sensitivity 0.871 > 0.782
Positive Predictive Value 0.946 > 0.919
Total TP 88 > 79
Total TN 45963 < 45970
Total FP 10 < 17
Total FP CONTRA 0 = 0
Total FP INCONS 5 < 7
Total FP COMP 5 < 10
Total FN 13 < 22
P-value 0.0

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Performance plots


  1. Comparison of performance of CentroidAlifold(20) and PPfold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(20) and PPfold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(20) and PPfold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(20) and PPfold(seed)).

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Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(20)

Total Base Pair Counts
Total TP 88
Total TN 45963
Total FP 10
Total FP CONTRA 0
Total FP INCONS 5
Total FP COMP 5
Total FN 13
Total Scores
MCC 0.908
Average MCC ± 95% Confidence Intervals 0.908 ±
Sensitivity 0.871
Positive Predictive Value 0.946
Nr of predictions 1

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2. Individual counts for CentroidAlifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
SRP_00182 0.91 0.87 0.95 88 45963 10 0 5 5 13

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Performance of PPfold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 79
Total TN 45970
Total FP 17
Total FP CONTRA 0
Total FP INCONS 7
Total FP COMP 10
Total FN 22
Total Scores
MCC 0.847
Average MCC ± 95% Confidence Intervals 0.847 ±
Sensitivity 0.782
Positive Predictive Value 0.919
Nr of predictions 1

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
SRP_00182 0.85 0.78 0.92 79 45970 17 0 7 10 22

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.