CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of HotKnots - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for HotKnots & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric HotKnots RNASampler(seed)
MCC 0.640 > 0.523
Average MCC ± 95% Confidence Intervals 0.640 ± > 0.523 ±
Sensitivity 0.615 > 0.436
Positive Predictive Value 0.667 > 0.630
Total TP 24 > 17
Total TN 21909 < 21918
Total FP 25 > 15
Total FP CONTRA 3 > 2
Total FP INCONS 9 > 8
Total FP COMP 13 > 5
Total FN 15 < 22
P-value 0.0

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Performance plots


  1. Comparison of performance of HotKnots and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for HotKnots and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for HotKnots and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for HotKnots and RNASampler(seed)).

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Performance of HotKnots - scored higher in this pairwise comparison

1. Total counts & total scores for HotKnots

Total Base Pair Counts
Total TP 24
Total TN 21909
Total FP 25
Total FP CONTRA 3
Total FP INCONS 9
Total FP COMP 13
Total FN 15
Total Scores
MCC 0.640
Average MCC ± 95% Confidence Intervals 0.640 ±
Sensitivity 0.615
Positive Predictive Value 0.667
Nr of predictions 1

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2. Individual counts for HotKnots [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00620 0.64 0.62 0.67 24 21909 25 3 9 13 15

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 17
Total TN 21918
Total FP 15
Total FP CONTRA 2
Total FP INCONS 8
Total FP COMP 5
Total FN 22
Total Scores
MCC 0.523
Average MCC ± 95% Confidence Intervals 0.523 ±
Sensitivity 0.436
Positive Predictive Value 0.630
Nr of predictions 1

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00620 0.52 0.44 0.63 17 21918 15 2 8 5 22

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.