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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of HotKnots - scored higher in this pairwise comparison

  4. Performance of RSpredict(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for HotKnots & RSpredict(seed) [.zip] - may take several seconds...


Overview

Metric HotKnots RSpredict(seed)
MCC 0.640 > -0.002
Average MCC ± 95% Confidence Intervals 0.640 ± > -0.002 ±
Sensitivity 0.615 > 0.000
Positive Predictive Value 0.667 > 0.000
Total TP 24 > 0
Total TN 21909 < 21916
Total FP 25 < 33
Total FP CONTRA 3 > 2
Total FP INCONS 9 < 27
Total FP COMP 13 > 4
Total FN 15 < 39
P-value 0.0

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Performance plots


  1. Comparison of performance of HotKnots and RSpredict(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for HotKnots and RSpredict(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for HotKnots and RSpredict(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for HotKnots and RSpredict(seed)).

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Performance of HotKnots - scored higher in this pairwise comparison

1. Total counts & total scores for HotKnots

Total Base Pair Counts
Total TP 24
Total TN 21909
Total FP 25
Total FP CONTRA 3
Total FP INCONS 9
Total FP COMP 13
Total FN 15
Total Scores
MCC 0.640
Average MCC ± 95% Confidence Intervals 0.640 ±
Sensitivity 0.615
Positive Predictive Value 0.667
Nr of predictions 1

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2. Individual counts for HotKnots [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00620 0.64 0.62 0.67 24 21909 25 3 9 13 15

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Performance of RSpredict(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP 0
Total TN 21916
Total FP 33
Total FP CONTRA 2
Total FP INCONS 27
Total FP COMP 4
Total FN 39
Total Scores
MCC -0.002
Average MCC ± 95% Confidence Intervals -0.002 ±
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 1

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2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00620 0.00 0.00 0.00 0 21916 33 2 27 4 39

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.