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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of HotKnots - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & HotKnots [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) HotKnots
MCC 0.891 > 0.640
Average MCC ± 95% Confidence Intervals 0.891 ± > 0.640 ±
Sensitivity 0.795 > 0.615
Positive Predictive Value 1.000 > 0.667
Total TP 31 > 24
Total TN 21914 > 21909
Total FP 0 < 25
Total FP CONTRA 0 < 3
Total FP INCONS 0 < 9
Total FP COMP 0 < 13
Total FN 8 < 15
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and HotKnots. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and HotKnots).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and HotKnots. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and HotKnots).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 31
Total TN 21914
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 8
Total Scores
MCC 0.891
Average MCC ± 95% Confidence Intervals 0.891 ±
Sensitivity 0.795
Positive Predictive Value 1.000
Nr of predictions 1

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00620 0.89 0.79 1.00 31 21914 0 0 0 0 8

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Performance of HotKnots - scored lower in this pairwise comparison

1. Total counts & total scores for HotKnots

Total Base Pair Counts
Total TP 24
Total TN 21909
Total FP 25
Total FP CONTRA 3
Total FP INCONS 9
Total FP COMP 13
Total FN 15
Total Scores
MCC 0.640
Average MCC ± 95% Confidence Intervals 0.640 ±
Sensitivity 0.615
Positive Predictive Value 0.667
Nr of predictions 1

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2. Individual counts for HotKnots [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00620 0.64 0.62 0.67 24 21909 25 3 9 13 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.