Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
- Performance of Multilign(seed)
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(seed) & Multilign(seed) [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(seed) |
|
Multilign(seed) |
|---|
| MCC |
0.806 |
>
|
0.759 |
| Average MCC ± 95% Confidence Intervals |
0.834
±
0.150
|
>
|
0.781
±
0.128
|
| Sensitivity |
0.781 |
>
|
0.752 |
| Positive Predictive Value |
0.832 |
>
|
0.767 |
| Total TP |
495 |
>
|
477 |
| Total TN |
360790 |
>
|
360763 |
| Total FP |
187 |
<
|
227 |
| Total FP CONTRA |
17 |
<
|
30 |
| Total FP INCONS |
83 |
<
|
115 |
| Total FP COMP |
87 |
>
|
82 |
| Total FN |
139 |
<
|
157 |
| P-value |
0.0 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(seed) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Multilign(seed)).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Multilign(seed)).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Multilign(seed)).
Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(seed)
| Total Base Pair Counts |
|---|
| Total TP |
495 |
| Total TN |
360790 |
| Total FP |
187 |
| Total FP CONTRA |
17 |
| Total FP INCONS |
83 |
| Total FP COMP |
87 |
| Total FN |
139 |
| Total Scores |
|---|
| MCC |
0.806 |
| Average MCC ± 95% Confidence Intervals |
0.834
±
0.150
|
| Sensitivity |
0.781 |
| Positive Predictive Value |
0.832 |
| Nr of predictions |
9 |
Performance of Multilign(seed)
- scored lower in this pairwise comparison
1. Total counts & total scores for Multilign(seed)
| Total Base Pair Counts |
|---|
| Total TP |
477 |
| Total TN |
360763 |
| Total FP |
227 |
| Total FP CONTRA |
30 |
| Total FP INCONS |
115 |
| Total FP COMP |
82 |
| Total FN |
157 |
| Total Scores |
|---|
| MCC |
0.759 |
| Average MCC ± 95% Confidence Intervals |
0.781
±
0.128
|
| Sensitivity |
0.752 |
| Positive Predictive Value |
0.767 |
| Nr of predictions |
9 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
