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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(seed) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(seed) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric PPfold(seed) CMfinder(20)
MCC 0.847 > 0.524
Average MCC ± 95% Confidence Intervals 0.847 ± > 0.524 ±
Sensitivity 0.782 > 0.376
Positive Predictive Value 0.919 > 0.731
Total TP 79 > 38
Total TN 45970 < 46004
Total FP 17 > 14
Total FP CONTRA 0 = 0
Total FP INCONS 7 < 14
Total FP COMP 10 > 0
Total FN 22 < 63
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(seed) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(seed) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(seed) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(seed) and CMfinder(20)).

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Performance of PPfold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 79
Total TN 45970
Total FP 17
Total FP CONTRA 0
Total FP INCONS 7
Total FP COMP 10
Total FN 22
Total Scores
MCC 0.847
Average MCC ± 95% Confidence Intervals 0.847 ±
Sensitivity 0.782
Positive Predictive Value 0.919
Nr of predictions 1

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
SRP_00182 0.85 0.78 0.92 79 45970 17 0 7 10 22

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 38
Total TN 46004
Total FP 14
Total FP CONTRA 0
Total FP INCONS 14
Total FP COMP 0
Total FN 63
Total Scores
MCC 0.524
Average MCC ± 95% Confidence Intervals 0.524 ±
Sensitivity 0.376
Positive Predictive Value 0.731
Nr of predictions 1

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
SRP_00182 0.52 0.38 0.73 38 46004 14 0 14 0 63

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.