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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(seed) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(seed) & NanoFolder [.zip] - may take several seconds...


Overview

Metric PPfold(seed) NanoFolder
MCC 0.950 > -0.003
Average MCC ± 95% Confidence Intervals 0.950 ± > -0.003 ±
Sensitivity 0.902 > 0.000
Positive Predictive Value 1.000 > 0.000
Total TP 37 > 0
Total TN 23183 > 23133
Total FP 2 < 89
Total FP CONTRA 0 < 30
Total FP INCONS 0 < 57
Total FP COMP 2 = 2
Total FN 4 < 41
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(seed) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(seed) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(seed) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(seed) and NanoFolder).

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Performance of PPfold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 37
Total TN 23183
Total FP 2
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 2
Total FN 4
Total Scores
MCC 0.950
Average MCC ± 95% Confidence Intervals 0.950 ±
Sensitivity 0.902
Positive Predictive Value 1.000
Nr of predictions 1

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00816

R2_retro_el links to Rfam database...

0.95 0.90 1.00 37 23183 2 0 0 2 4

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 0
Total TN 23133
Total FP 89
Total FP CONTRA 30
Total FP INCONS 57
Total FP COMP 2
Total FN 41
Total Scores
MCC -0.003
Average MCC ± 95% Confidence Intervals -0.003 ±
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 1

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00816

R2_retro_el links to Rfam database...

0.00 0.00 0.00 0 23133 89 30 57 2 41

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.

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