CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & NanoFolder [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) NanoFolder
MCC 0.698 > 0.075
Average MCC ± 95% Confidence Intervals 0.689 ± 2.112 > 0.078 ± 1.020
Sensitivity 0.600 > 0.113
Positive Predictive Value 0.814 > 0.054
Total TP 48 > 9
Total TN 45106 > 44997
Total FP 21 < 169
Total FP CONTRA 2 < 59
Total FP INCONS 9 < 100
Total FP COMP 10 = 10
Total FN 32 < 71
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and NanoFolder).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 48
Total TN 45106
Total FP 21
Total FP CONTRA 2
Total FP INCONS 9
Total FP COMP 10
Total FN 32
Total Scores
MCC 0.698
Average MCC ± 95% Confidence Intervals 0.689 ± 2.112
Sensitivity 0.600
Positive Predictive Value 0.814
Nr of predictions 2

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00620 0.52 0.44 0.63 17 21918 15 2 8 5 22
RFA_00816 0.86 0.76 0.97 31 23188 6 0 1 5 10

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 9
Total TN 44997
Total FP 169
Total FP CONTRA 59
Total FP INCONS 100
Total FP COMP 10
Total FN 71
Total Scores
MCC 0.075
Average MCC ± 95% Confidence Intervals 0.078 ± 1.020
Sensitivity 0.113
Positive Predictive Value 0.054
Nr of predictions 2

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00620 0.16 0.23 0.11 9 21864 80 29 43 8 30
RFA_00816 0.00 0.00 0.00 0 23133 89 30 57 2 41

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.