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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of Multilign(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & Multilign(20) [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) Multilign(20)
MCC 0.755 > 0.653
Average MCC ± 95% Confidence Intervals 0.755 ± > 0.653 ±
Sensitivity 0.739 > 0.477
Positive Predictive Value 0.774 < 0.894
Total TP 65 > 42
Total TN 36231 < 36268
Total FP 20 > 5
Total FP CONTRA 2 > 0
Total FP INCONS 17 > 5
Total FP COMP 1 > 0
Total FN 23 < 46
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and Multilign(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and Multilign(20)).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 65
Total TN 36231
Total FP 20
Total FP CONTRA 2
Total FP INCONS 17
Total FP COMP 1
Total FN 23
Total Scores
MCC 0.755
Average MCC ± 95% Confidence Intervals 0.755 ±
Sensitivity 0.739
Positive Predictive Value 0.774
Nr of predictions 1

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
SRP_00308 0.76 0.74 0.77 65 36231 20 2 17 1 23

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Performance of Multilign(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 42
Total TN 36268
Total FP 5
Total FP CONTRA 0
Total FP INCONS 5
Total FP COMP 0
Total FN 46
Total Scores
MCC 0.653
Average MCC ± 95% Confidence Intervals 0.653 ±
Sensitivity 0.477
Positive Predictive Value 0.894
Nr of predictions 1

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
SRP_00308 0.65 0.48 0.89 42 36268 5 0 5 0 46

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.