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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & NanoFolder [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) NanoFolder
MCC 0.834 > 0.088
Average MCC ± 95% Confidence Intervals 0.878 ± 1.554 > 0.069 ± 0.906
Sensitivity 0.822 > 0.116
Positive Predictive Value 0.848 > 0.070
Total TP 106 > 15
Total TN 59410 > 59322
Total FP 34 < 201
Total FP CONTRA 2 < 48
Total FP INCONS 17 < 150
Total FP COMP 15 > 3
Total FN 23 < 114
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and NanoFolder).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 106
Total TN 59410
Total FP 34
Total FP CONTRA 2
Total FP INCONS 17
Total FP COMP 15
Total FN 23
Total Scores
MCC 0.834
Average MCC ± 95% Confidence Intervals 0.878 ± 1.554
Sensitivity 0.822
Positive Predictive Value 0.848
Nr of predictions 2

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00816 1.00 1.00 1.00 41 23179 14 0 0 14 0
SRP_00308 0.76 0.74 0.77 65 36231 20 2 17 1 23

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 15
Total TN 59322
Total FP 201
Total FP CONTRA 48
Total FP INCONS 150
Total FP COMP 3
Total FN 114
Total Scores
MCC 0.088
Average MCC ± 95% Confidence Intervals 0.069 ± 0.906
Sensitivity 0.116
Positive Predictive Value 0.070
Nr of predictions 2

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00816 0.00 0.00 0.00 0 23133 89 30 57 2 41
SRP_00308 0.14 0.17 0.12 15 36189 112 18 93 1 73

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.