CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Afold - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for Afold & RNASLOpt [.zip] - may take several seconds...


Overview

Metric Afold RNASLOpt
MCC 0.385 > 0.000
Average MCC ± 95% Confidence Intervals 0.385 ± > 0.000 ±
Sensitivity 0.358 > 0.000
Positive Predictive Value 0.415 > 0.000
Total TP 93 > 0
Total TN 456266 < 456490
Total FP 153 > 0
Total FP CONTRA 18 > 0
Total FP INCONS 113 > 0
Total FP COMP 22 > 0
Total FN 167 < 260
P-value 0.0

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Performance plots


  1. Comparison of performance of Afold and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Afold and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Afold and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Afold and RNASLOpt).

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Performance of Afold - scored higher in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP 93
Total TN 456266
Total FP 153
Total FP CONTRA 18
Total FP INCONS 113
Total FP COMP 22
Total FN 167
Total Scores
MCC 0.385
Average MCC ± 95% Confidence Intervals 0.385 ±
Sensitivity 0.358
Positive Predictive Value 0.415
Nr of predictions 1

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2. Individual counts for Afold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.39 0.36 0.42 93 456266 153 18 113 22 167

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 0
Total TN 456490
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 260
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ±
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 1

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.00 0.00 0.00 0 456490 0 0 0 0 260

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.