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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(20) Carnac(seed)
MCC 0.906 > 0.729
Average MCC ± 95% Confidence Intervals 0.906 ± > 0.729 ±
Sensitivity 0.860 > 0.570
Positive Predictive Value 0.954 > 0.932
Total TP 394 > 261
Total TN 1085188 < 1085321
Total FP 51 > 35
Total FP CONTRA 6 = 6
Total FP INCONS 13 = 13
Total FP COMP 32 > 16
Total FN 64 < 197
P-value 0.0

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Performance plots


  1. Comparison of performance of CentroidAlifold(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(20) and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(20) and Carnac(seed)).

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Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(20)

Total Base Pair Counts
Total TP 394
Total TN 1085188
Total FP 51
Total FP CONTRA 6
Total FP INCONS 13
Total FP COMP 32
Total FN 64
Total Scores
MCC 0.906
Average MCC ± 95% Confidence Intervals 0.906 ±
Sensitivity 0.860
Positive Predictive Value 0.954
Nr of predictions 1

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2. Individual counts for CentroidAlifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.91 0.86 0.95 394 1085188 51 6 13 32 64

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 261
Total TN 1085321
Total FP 35
Total FP CONTRA 6
Total FP INCONS 13
Total FP COMP 16
Total FN 197
Total Scores
MCC 0.729
Average MCC ± 95% Confidence Intervals 0.729 ±
Sensitivity 0.570
Positive Predictive Value 0.932
Nr of predictions 1

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.73 0.57 0.93 261 1085321 35 6 13 16 197

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.