CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(seed) & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(seed) Murlet(seed)
MCC 0.863 > 0.642
Average MCC ± 95% Confidence Intervals 0.863 ± > 0.642 ±
Sensitivity 0.809 > 0.606
Positive Predictive Value 0.921 > 0.681
Total TP 351 > 263
Total TN 977520 > 977515
Total FP 61 < 145
Total FP CONTRA 3 < 6
Total FP INCONS 27 < 117
Total FP COMP 31 > 22
Total FN 83 < 171
P-value 0.0

^top




Performance plots


  1. Comparison of performance of CentroidAlifold(seed) and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(seed) and Murlet(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(seed) and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(seed) and Murlet(seed)).

^top





Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP 351
Total TN 977520
Total FP 61
Total FP CONTRA 3
Total FP INCONS 27
Total FP COMP 31
Total FN 83
Total Scores
MCC 0.863
Average MCC ± 95% Confidence Intervals 0.863 ±
Sensitivity 0.809
Positive Predictive Value 0.921
Nr of predictions 1

^top



2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_01343 0.86 0.81 0.92 351 977520 61 3 27 31 83

^top



Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 263
Total TN 977515
Total FP 145
Total FP CONTRA 6
Total FP INCONS 117
Total FP COMP 22
Total FN 171
Total Scores
MCC 0.642
Average MCC ± 95% Confidence Intervals 0.642 ±
Sensitivity 0.606
Positive Predictive Value 0.681
Nr of predictions 1

^top



2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_01343 0.64 0.61 0.68 263 977515 145 6 117 22 171

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.