CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidFold - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidFold & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric CentroidFold Carnac(seed)
MCC 0.793 > 0.729
Average MCC ± 95% Confidence Intervals 0.793 ± > 0.729 ±
Sensitivity 0.758 > 0.570
Positive Predictive Value 0.830 < 0.932
Total TP 347 > 261
Total TN 1085183 < 1085321
Total FP 108 > 35
Total FP CONTRA 8 > 6
Total FP INCONS 63 > 13
Total FP COMP 37 > 16
Total FN 111 < 197
P-value 0.0

^top




Performance plots


  1. Comparison of performance of CentroidFold and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidFold and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidFold and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidFold and Carnac(seed)).

^top





Performance of CentroidFold - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidFold

Total Base Pair Counts
Total TP 347
Total TN 1085183
Total FP 108
Total FP CONTRA 8
Total FP INCONS 63
Total FP COMP 37
Total FN 111
Total Scores
MCC 0.793
Average MCC ± 95% Confidence Intervals 0.793 ±
Sensitivity 0.758
Positive Predictive Value 0.830
Nr of predictions 1

^top



2. Individual counts for CentroidFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.79 0.76 0.83 347 1085183 108 8 63 37 111

^top



Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 261
Total TN 1085321
Total FP 35
Total FP CONTRA 6
Total FP INCONS 13
Total FP COMP 16
Total FN 197
Total Scores
MCC 0.729
Average MCC ± 95% Confidence Intervals 0.729 ±
Sensitivity 0.570
Positive Predictive Value 0.932
Nr of predictions 1

^top



2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.73 0.57 0.93 261 1085321 35 6 13 16 197

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.