CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold Carnac(seed)
MCC 0.952 > 0.729
Average MCC ± 95% Confidence Intervals 0.952 ± > 0.729 ±
Sensitivity 0.924 > 0.570
Positive Predictive Value 0.981 > 0.932
Total TP 423 > 261
Total TN 1085170 < 1085321
Total FP 15 < 35
Total FP CONTRA 3 < 6
Total FP INCONS 5 < 13
Total FP COMP 7 < 16
Total FN 35 < 197
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and Carnac(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 423
Total TN 1085170
Total FP 15
Total FP CONTRA 3
Total FP INCONS 5
Total FP COMP 7
Total FN 35
Total Scores
MCC 0.952
Average MCC ± 95% Confidence Intervals 0.952 ±
Sensitivity 0.924
Positive Predictive Value 0.981
Nr of predictions 1

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.95 0.92 0.98 423 1085170 15 3 5 7 35

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 261
Total TN 1085321
Total FP 35
Total FP CONTRA 6
Total FP INCONS 13
Total FP COMP 16
Total FN 197
Total Scores
MCC 0.729
Average MCC ± 95% Confidence Intervals 0.729 ±
Sensitivity 0.570
Positive Predictive Value 0.932
Nr of predictions 1

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.73 0.57 0.93 261 1085321 35 6 13 16 197

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.