CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Contrafold - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Contrafold & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric Contrafold Mastr(seed)
MCC 0.425 > 0.000
Average MCC ± 95% Confidence Intervals 0.425 ± 0.351 > 0.000 ± 0.000
Sensitivity 0.413 > 0.000
Positive Predictive Value 0.437 > 0.000
Total TP 605 > 0
Total TN 4973395 < 4974778
Total FP 990 > 0
Total FP CONTRA 122 > 0
Total FP INCONS 656 > 0
Total FP COMP 212 > 0
Total FN 861 < 1466
P-value 0.0

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Performance plots


  1. Comparison of performance of Contrafold and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Contrafold and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Contrafold and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Contrafold and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Contrafold and Mastr(seed)).

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Performance of Contrafold - scored higher in this pairwise comparison

1. Total counts & total scores for Contrafold

Total Base Pair Counts
Total TP 605
Total TN 4973395
Total FP 990
Total FP CONTRA 122
Total FP INCONS 656
Total FP COMP 212
Total FN 861
Total Scores
MCC 0.425
Average MCC ± 95% Confidence Intervals 0.425 ± 0.351
Sensitivity 0.413
Positive Predictive Value 0.437
Nr of predictions 3

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2. Individual counts for Contrafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00306 0.28 0.28 0.29 129 1445402 388 63 256 69 333
CRW_00379 0.43 0.42 0.44 223 2126443 372 38 249 85 311
CRW_00800 0.57 0.54 0.60 253 1401550 230 21 151 58 217

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 4974778
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 1466
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 3

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00306 0.00 0.00 0.00 0 1445850 0 0 0 0 462
CRW_00379 0.00 0.00 0.00 0 2126953 0 0 0 0 534
CRW_00800 0.00 0.00 0.00 0 1401975 0 0 0 0 470

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.