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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(seed) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric MXScarna(seed) Mastr(seed)
MCC 0.375 > 0.000
Average MCC ± 95% Confidence Intervals 0.375 ± 0.110 > 0.000 ± 0.000
Sensitivity 0.333 > 0.000
Positive Predictive Value 0.423 > 0.000
Total TP 488 > 0
Total TN 4973623 < 4974778
Total FP 841 > 0
Total FP CONTRA 132 > 0
Total FP INCONS 535 > 0
Total FP COMP 174 > 0
Total FN 978 < 1466
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(seed) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(seed) and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MXScarna(seed) and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(seed) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(seed) and Mastr(seed)).

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Performance of MXScarna(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(seed)

Total Base Pair Counts
Total TP 488
Total TN 4973623
Total FP 841
Total FP CONTRA 132
Total FP INCONS 535
Total FP COMP 174
Total FN 978
Total Scores
MCC 0.375
Average MCC ± 95% Confidence Intervals 0.375 ± 0.110
Sensitivity 0.333
Positive Predictive Value 0.423
Nr of predictions 3

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2. Individual counts for MXScarna(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00306 0.42 0.39 0.46 181 1445456 267 46 167 54 281
CRW_00379 0.36 0.32 0.41 170 2126540 318 50 193 75 364
CRW_00800 0.34 0.29 0.39 137 1401627 256 36 175 45 333

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 4974778
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 1466
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 3

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00306 0.00 0.00 0.00 0 1445850 0 0 0 0 462
CRW_00379 0.00 0.00 0.00 0 2126953 0 0 0 0 534
CRW_00800 0.00 0.00 0.00 0 1401975 0 0 0 0 470

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.