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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of IPknot - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & IPknot [.zip] - may take several seconds...


Overview

Metric Murlet(seed) IPknot
MCC 0.642 > 0.499
Average MCC ± 95% Confidence Intervals 0.642 ± > 0.499 ±
Sensitivity 0.606 > 0.419
Positive Predictive Value 0.681 > 0.595
Total TP 263 > 182
Total TN 977515 < 977595
Total FP 145 > 134
Total FP CONTRA 6 < 16
Total FP INCONS 117 > 108
Total FP COMP 22 > 10
Total FN 171 < 252
P-value 0.0

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Performance plots


  1. Comparison of performance of Murlet(seed) and IPknot. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and IPknot).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and IPknot. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and IPknot).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 263
Total TN 977515
Total FP 145
Total FP CONTRA 6
Total FP INCONS 117
Total FP COMP 22
Total FN 171
Total Scores
MCC 0.642
Average MCC ± 95% Confidence Intervals 0.642 ±
Sensitivity 0.606
Positive Predictive Value 0.681
Nr of predictions 1

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_01343

SSU_rRNA_archaea links to Rfam database...

0.64 0.61 0.68 263 977515 145 6 117 22 171

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Performance of IPknot - scored lower in this pairwise comparison

1. Total counts & total scores for IPknot

Total Base Pair Counts
Total TP 182
Total TN 977595
Total FP 134
Total FP CONTRA 16
Total FP INCONS 108
Total FP COMP 10
Total FN 252
Total Scores
MCC 0.499
Average MCC ± 95% Confidence Intervals 0.499 ±
Sensitivity 0.419
Positive Predictive Value 0.595
Nr of predictions 1

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2. Individual counts for IPknot [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_01343

SSU_rRNA_archaea links to Rfam database...

0.50 0.42 0.59 182 977595 134 16 108 10 252

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.

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