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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of ProbKnot - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & ProbKnot [.zip] - may take several seconds...


Overview

Metric Murlet(seed) ProbKnot
MCC 0.642 > 0.369
Average MCC ± 95% Confidence Intervals 0.642 ± > 0.369 ±
Sensitivity 0.606 > 0.364
Positive Predictive Value 0.681 > 0.375
Total TP 263 > 158
Total TN 977515 > 977480
Total FP 145 < 279
Total FP CONTRA 6 < 40
Total FP INCONS 117 < 223
Total FP COMP 22 > 16
Total FN 171 < 276
P-value 0.0

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Performance plots


  1. Comparison of performance of Murlet(seed) and ProbKnot. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and ProbKnot).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and ProbKnot. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and ProbKnot).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 263
Total TN 977515
Total FP 145
Total FP CONTRA 6
Total FP INCONS 117
Total FP COMP 22
Total FN 171
Total Scores
MCC 0.642
Average MCC ± 95% Confidence Intervals 0.642 ±
Sensitivity 0.606
Positive Predictive Value 0.681
Nr of predictions 1

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_01343 0.64 0.61 0.68 263 977515 145 6 117 22 171

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Performance of ProbKnot - scored lower in this pairwise comparison

1. Total counts & total scores for ProbKnot

Total Base Pair Counts
Total TP 158
Total TN 977480
Total FP 279
Total FP CONTRA 40
Total FP INCONS 223
Total FP COMP 16
Total FN 276
Total Scores
MCC 0.369
Average MCC ± 95% Confidence Intervals 0.369 ±
Sensitivity 0.364
Positive Predictive Value 0.375
Nr of predictions 1

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2. Individual counts for ProbKnot [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_01343 0.37 0.36 0.38 158 977480 279 40 223 16 276

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.