CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of RNAfold - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & RNAfold [.zip] - may take several seconds...


Overview

Metric Murlet(seed) RNAfold
MCC 0.642 > 0.372
Average MCC ± 95% Confidence Intervals 0.642 ± > 0.372 ±
Sensitivity 0.606 > 0.369
Positive Predictive Value 0.681 > 0.376
Total TP 263 > 160
Total TN 977515 > 977476
Total FP 145 < 278
Total FP CONTRA 6 < 42
Total FP INCONS 117 < 223
Total FP COMP 22 > 13
Total FN 171 < 274
P-value 0.0

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Performance plots


  1. Comparison of performance of Murlet(seed) and RNAfold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and RNAfold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and RNAfold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and RNAfold).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 263
Total TN 977515
Total FP 145
Total FP CONTRA 6
Total FP INCONS 117
Total FP COMP 22
Total FN 171
Total Scores
MCC 0.642
Average MCC ± 95% Confidence Intervals 0.642 ±
Sensitivity 0.606
Positive Predictive Value 0.681
Nr of predictions 1

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_01343 0.64 0.61 0.68 263 977515 145 6 117 22 171

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Performance of RNAfold - scored lower in this pairwise comparison

1. Total counts & total scores for RNAfold

Total Base Pair Counts
Total TP 160
Total TN 977476
Total FP 278
Total FP CONTRA 42
Total FP INCONS 223
Total FP COMP 13
Total FN 274
Total Scores
MCC 0.372
Average MCC ± 95% Confidence Intervals 0.372 ±
Sensitivity 0.369
Positive Predictive Value 0.376
Nr of predictions 1

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2. Individual counts for RNAfold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_01343 0.37 0.37 0.38 160 977476 278 42 223 13 274

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.